氢溴酸非诺特罗
|
|
|
- CAS号:
- 1944-12-3
- 英文名:
- FENOTEROL HYDROBROMIDE
- 英文别名:
- Airum;Emitex;Ugacor;berotec;th1165a;Siobetec;Dosberotec;partusisten;FENOTEROL HBR;fenoterolbromide
- 中文名:
- 氢溴酸非诺特罗
- 中文别名:
- 氢溴酸芬忒醇;氢溴酸非诺特罗;氢溴酸菲诺特罗;菲诺特洛氢溴酸盐;氢溴酸非诺特罗 标准品;氢溴酸菲诺特罗标准溶液;非诺特罗峰鉴别 EP标准品;甲醇中菲诺特罗溶液标准物质;氢溴酸非诺特罗 EP标准品;氢溴酸非诺特罗/酚丙喘宁芬忒醇
- CBNumber:
- CB0210728
- 分子式:
- C17H22BrNO4
- 分子量:
- 384.26
- MOL File:
- 1944-12-3.mol
|
|
|
氢溴酸非诺特罗化学性质
-
熔点:
-
226-228°C
-
|
-
储存条件:
-
2-8°C
-
|
-
溶解度:
-
Soluble in water and in ethanol (96 per cent).
-
|
-
颜色:
-
White to Off-White
-
|
氢溴酸非诺特罗性质、用途与生产工艺
Fenoterol hydrobromide (Phenoterol)是fenoterol的氢溴酸盐。Fenoterol是β2 adrenoreceptor激动剂，具有支气管扩张活性。
| Target | Value |
β2 adrenoreceptor
()
|
Fenoterol (1 μM; pre-incubated 30 minutes) treatment reduces AICAR-induced AMPK activation, NF-κB activation and TNF-α release, and also significantly downregulates the elevated phosphorylation levels of AMPK.
Fenoterol inhibits lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells.
Fenoterol is also a potent exosome biogenesis and/or secretion activator in PC cells.
Western Blot Analysis
|
Cell Line:
|
THP-1 cells stimulated with AICAR
|
|
Concentration:
|
1 μM
|
|
Incubation Time:
|
Pre-incubated 30 minutes
|
|
Result:
|
Significantly downregulated the elevated phosphorylation levels of AMPK.
|
Fenoterol (0.7 mg/kg; intraperitoneal injection; twice a day; for 3 weeks) treatment suppresses mechanical allodynia during chronic treatment.
|
Animal Model:
|
Male C57BL/6J mice (6 weeks old) with neuropathy
|
|
Dosage:
|
0.7 mg/kg
|
|
Administration:
|
Intraperitoneal injection; twice a day; for 3 weeks
|
|
Result:
|
Alleviated neuropathic allodynia during chronic treatment.
|
用途
校准仪器和装置；评价方法；工作标准；质量保证/质量控制
氢溴酸非诺特罗
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-B0976A | 氢溴酸非诺特罗
Fenoterol hydrobromide | 1944-12-3 | 100mg | 700元 |
| 2024/01/25 | HY-B0976A | 氢溴酸非诺特罗
Fenoterol hydrobromide | 1944-12-3 | 10mM * 1mLin DMSO | 930元 |
氢溴酸非诺特罗
生产厂家
全球有 117家供应商
氢溴酸非诺特罗国内生产厂家
1944-12-3, 氢溴酸非诺特罗 相关搜索:
- Adrenoceptor
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Aromatics
- Amines
- 高端化学
- 对照品
- 标准品
- 医药原料
- 法医和兽医标准品
- 瘦肉精类
- 分析标准品
- beta2-adrenoceptor agonist; bronchodilator.
- C17H22BrNO4
- 氢溴酸菲诺特罗/非诺特罗氢溴酸盐
- 氢溴酸非诺特罗 EP标准品
- 非诺特罗峰鉴别 EP标准品
- 氢溴酸非诺特罗 标准品
- 菲诺特洛氢溴酸盐
- 氢溴酸非诺特罗/酚丙喘宁芬忒醇
- 氢溴酸菲诺特罗标准溶液
- 氢溴酸菲诺特罗
- 5-[1-羟基-2-[[2-(4-羟基苯基)-1-甲基乙基]氨基]乙基]-1,3-苯二醇
- 氢溴酸非诺特罗非诺特罗 氢溴酸盐
- 甲醇中菲诺特罗溶液标准物质
- 氢溴酸非诺特罗
- 氢溴酸芬忒醇
- 1944-12-3
- FENOTEROL HYDROBROMIDE USP/EP/BP
- Fenoterol in Methanol
- Fenoterol HBr (Mixture of Diastereomers)
- Fenoterol for peak identification CRS
- Fenoterol hydrobromide CRS
- 1,3-Benzenediol,5-[1-hydroxy-2-[[2-(4-hydroxyphenyl)-1-Methylethyl]aMino]ethyl]-, hydrobroMide(1:1)
- Fenoterol HydrobroMide USP
- Fenoterol solution
- Fenoterol hydrobromide,2-(3,5-Dihydroxyphenyl)-2-hydroxy-2′-(4-hydroxyphenyl)-1′-methyldiethylamine hydrobromide
- 5-[1-Hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-1,3-benzenediol hydrobromide
- FenoteroleHydrobromide
- Ugacor
- Siobetec
- Emitex
- 5-[1-hydroxy-2-[1-(4-hydroxyphenyl)propan-2-ylamino]ethyl]benzene-1,3-diol hydrobromide
- Dosberotec
- Benzyl alcohol, 3,5-dihydroxy-α-[[(p-hydroxy-α-methylphenethyl)amino]methyl]-, hydrobromide (8CI)
- Airum
- 3,5-Dihydroxy-α-[[(p-hydroxy-α-methylphenethyl)amino]methyl]benzyl alc. monohydrobromide
- 3,5-Dihydroxy-α-[(p-hydroxy-α-methylphenethyl)amino]methylbenzyl alcohol hydrobromide
- 1,3-Benzenediol, 5-[1-hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-, hydrobromide
- 1-(p-Hydroxyphenyl)-2-(β-3',5'-dihydroxyphenyl-β-hydroxy)ethylaminopropane hydrobromide
- 1-(3,5-Dihydroxyphenyl)-2-[2-(3-p-hydroxyphenyl)propylamino]ethanol hydrobromide
- Fenoterolhydrobromid
- 5-[1-hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]resorcinol hydrobromide
- th1165a
- phenoterolhydrobromide
- partusisten
- fenoterolbromide
- berotechydrobromide