非诺特罗
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- CAS号:
- 13392-18-2
- 英文名:
- Fenoterol
- 英文别名:
- lcohol;Th 1165;opropane;FENOTEROL;Phenoterol;AURORA KA-7877;Fenoterol USP/EP/BP;Fenoterol (Th-1165a;Fenoterol & Fenoterol Hydrobromide;1-(3,5-Dihydroxyphenyl)-2-[[1-(4-hydroxybenzyl)ethyl]amino]ethanol
- 中文名:
- 非诺特罗
- 中文别名:
- 非诺特罗;非诺特罗氢溴酸盐;甲醇中非诺特罗标准溶液;5-[1-羟基-2-[[2-(4-羟基苯基)-1-甲基乙基]氨基]乙基]-1,3-苯二酚
- CBNumber:
- CB6215967
- 分子式:
- C17H21NO4
- 分子量:
- 303.35
- MOL File:
- 13392-18-2.mol
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非诺特罗化学性质
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熔点:
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181-183°C
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沸点:
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566.0±45.0 °C(Predicted)
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密度:
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1.289±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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酸度系数(pKa):
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pKa 8.5 (Uncertain);10.0 (Uncertain)
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CAS 数据库:
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13392-18-2(CAS DataBase Reference)
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非诺特罗性质、用途与生产工艺
Fenoterol (Phenoterol) 是β2 adrenoreceptor激动剂，具有支气管扩张活性。
| Target | Value |
β2 adrenoreceptor
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Fenoterol (1 μM; pre-incubated 30 minutes) treatment reduces AICAR-induced AMPK activation, NF-κB activation and TNF-α release, and also significantly downregulates the elevated phosphorylation levels of AMPK.
Fenoterol inhibits lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells.
Fenoterol is also a potent exosome biogenesis and/or secretion activator in PC cells.
Western Blot Analysis
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Cell Line:
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THP-1 cells stimulated with AICAR
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Concentration:
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1 μM
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Incubation Time:
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Pre-incubated 30 minutes
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Result:
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Significantly downregulated the elevated phosphorylation levels of AMPK.
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Fenoterol (0.7 mg/kg; intraperitoneal injection; twice a day; for 3 weeks) treatment suppresses mechanical allodynia during chronic treatment.
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Animal Model:
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Male C57BL/6J mice (6 weeks old) with neuropathy
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Dosage:
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0.7 mg/kg
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Administration:
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Intraperitoneal injection; twice a day; for 3 weeks
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Result:
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Alleviated neuropathic allodynia during chronic treatment.
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非诺特罗
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-B0976 | Fenoterol | | 5 mg | 470元 |
| 2024/01/25 | HY-B0976 | Fenoterol | | 10 mg | 750元 |
非诺特罗
生产厂家
全球有 75家供应商
非诺特罗国内生产厂家
13392-18-2, 非诺特罗 相关搜索:
- API
- FDA批准的配体
- 对照品
- 平喘药物
- 瘦肉精类
- 甲醇中非诺特罗标准溶液
- 5-[1-羟基-2-[[2-(4-羟基苯基)-1-甲基乙基]氨基]乙基]-1,3-苯二酚
- 非诺特罗
- 非诺特罗氢溴酸盐
- 13392-18-2
- Beta Receptor,Inhibitor,Fenoterol,β2-adrenoceptor,Th1165,antiallergic,exosome,inhibit,sympathomimetic,Phenoterol,Adrenergic Receptor,anti-inflammatory,bronchodilator,Th-1165,Th 1165
- Fenoterol (Th-1165a
- Fenoterol USP/EP/BP
- 5-[1-hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-1,3-benzenediol
- 1-(3,5-dihydroxyphenyl)-1-hydroxy-2-[(4-hydroxyphenyl)isopropylamino]ethane
- FENOTEROL
- AURORA KA-7877
- Fenoterol & Fenoterol Hydrobromide
- 3,5-Dihydroxy-α-[[(4-hydroxy-α-methylphenethyl)amino]methyl]benzyl alcohol
- Th 1165
- Phenoterol
- Benzyl alcohol, 3,5-dihydroxy-α-[[(p-hydroxy-α-methylphenethyl)amino]methyl]- (8CI)
- 3,5-Dihydroxy-α-[p-hydroxy-α-methylphenethylamino]methylbenzyl alcohol
- 1,3-Benzenediol, 5-[1-hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-
- 1-(3,5-Dihydroxyphenyl)-2-[[1-(4-hydroxybenzyl)ethyl]amino]ethanol
- 1-(3,5-Dihydroxyphenyl)-2-(p-hydroxy-α-methylphenethylamino)ethanol
- 1-(3,5-Dihydroxyphenyl)-1-hydroxy-2-[1-(4-hydroxyphenyl)isopropyl]aminoethane
- opropane
- lcohol
- benzylalcohol,3,5-dihydroxy-alpha-(((p-hydroxy-alpha-methylphenethyl)amino)me
- 3,5-dihydroxy-alpha-(((p-hydroxy-alpha-methylphenethyl)amino)methyl)benzyla
- 1,3-benzenediol,5-(1-hydroxy-2-((2-(4-hydroxyphenyl)-1-methylethyl)amino)eth
- 1-(p-hydroxyphenyl)-2-((beta-hydroxy-beta-(3’,5’-dihydroxyphenyl))ethyl)amin