丁基硫
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- CAS号:
- 5072-26-4
- 英文名:
- DL-BUTHIONINE-[S,R]-SULFOXIMINE
- 英文别名:
- NSC 381100;butioninesulfoximine;buthioninesulfoximine;buthioninesulfoxamine;buthioninesulphoximine;DL-BUTHIONINE-SULFOXIMINE;DL-BUTHIONINE (S,R)-SULPHOXIME;DL-BUTHIONINE-[S,R]-SULFOXIMINE;DL-BUTHIONINE (R,S)-SULFOXIMINE;DL-Buthionine (S,R)-sulfoximine,99%
- 中文名:
- 丁基硫
- 中文别名:
- 丁基硫;DL-丁硫氨酸亚砜;丁硫胺酸亚砜胺(BSO);DL -丁硫氨酸亚砜亚胺;DL-丁硫氨酸-S,R-磺基;DL-丁硫氨酸-(S,R)-亚砜胺;DL-丁硫氨酸(S,R)-亚砜亚胺;D,L-蛋氨酸-(S,R)-亚磺酰亚胺;DL-丁硫氨酸-(S,R)-亚砜亚胺;DL-(3-氨基-4-羧丙基)-(S,R)-丁基硫氧亚胺
- CBNumber:
- CB4184630
- 分子式:
- C8H18N2O3S
- 分子量:
- 222.31
- MOL File:
- 5072-26-4.mol
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丁基硫化学性质
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熔点:
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215 °C (dec.)(lit.)
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沸点:
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382.3±52.0 °C(Predicted)
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密度:
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1.29±0.1 g/cm3(Predicted)
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储存条件:
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2-8°C
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溶解度:
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H2O: 50 mg/mL, clear, colorless
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形态:
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Fluffy Powder
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颜色:
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White
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Merck:
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13,1520
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BRN:
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2367136
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CAS 数据库:
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5072-26-4(CAS DataBase Reference)
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丁基硫性质、用途与生产工艺
DL-Buthionine-Sulfoximine (BSO, DL-Buthionine-(S,R)-sulfoximine)是一种 glutathione (GSH) 合成的抑制剂。
Buthionine sulfoximine is an analogs of methionine sulfoximine and inhibits gamma-glutamylcysteine synthetase about 20 times more effectively than prothionine sulfoximine and at least 100 times more effectively than methionine sulfoximine.
Treatment of mice bearing HT1080 and HT1080/DR4 xenografts with a continuous i.v infusion of nontoxic doses of D,L-Buthionine-(S,R)-sulfoximine (300 and 600 mg/kg/day) produce a 60% reduction of GSH plasma levels and greater than 95 % reduction in GSH tumor levels in both parental and multidrug-resistant tumors.
丁基硫
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-106376 | 丁基硫
DL-Buthionine-(S,R)-sulfoximine | 5072-26-4 | 50mg | 600元 |
| 2024/01/25 | HY-106376 | 丁基硫
DL-Buthionine-(S,R)-sulfoximine | 5072-26-4 | 10mM * 1mLin Water | 660元 |
丁基硫
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5072-26-4, 丁基硫 相关搜索:
- Substrates, Inducers, Inhibitors
- Fusarinine -C OrnithinesteraseMulti-Drug Resistance and Drug Metabolism
- Enzyme Inhibitors by Enzyme
- Drug and Xenobiotic Metabolism
- D to
- Sulfur & Selenium Compounds
- Glutathione S-Transferase Agents
- D to K
- Enzyme Inhibitors
- Enzymes, Inhibitors, and Substrates
- Enzyme Inhibitors by Enzyme
- Fusarinine -C Ornithinesterase
- BioChemical
- Biochemicals and Reagents
- CH3CH23SONHCH2CH2CHNH2CO2H
- C8H18N2O3S
- D,L-蛋氨酸-(S,R)-亚磺酰亚胺
- DL -丁硫氨酸亚砜亚胺
- DL-丁硫氨酸-S,R-磺基
- DL-丁硫氨酸-(S,R)-亚砜亚胺
- 丁硫胺酸亚砜胺(BSO)
- 丁基硫
- DL-丁硫氨酸亚砜
- DL-丁硫氨酸-(S,R)-亚砜胺
- DL-丁硫氨酸(S,R)-亚砜亚胺
- DL-(3-氨基-4-羧丙基)-(S,R)-丁基硫氧亚胺
- 5072-26-4
- BSO,DL Buthionine (S,R) sulfoximine,Buthionine sulfoximine,DLButhionine(S,R)sulfoximine,Inhibitor,inhibit,Ferroptosis
- 2-Amino-4-(butylsulfonimidoyl)butanoic acid
- D,L-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine)
- D,L-Buthionine-(S,R)-sulfoximine (Synonyms: Butionine sulfoximine)
- DL-Buthionine (S,R)-sulfoximine,99%
- 2-Amino-4-(S-butylsulfonimidoyl)butyric acid
- DL-Buthionine (S,R)-sulfoxiMine, 99% 500MG
- 2-Amino-4-(S-butylsulphonimidoyl)butanoic acid, S-(3-Amino-3-carboxypropyl)-S-butylsulphoximine
- S-butyl-DL-homocysteine (S,R)-sulfoximine
- S-(3-Amino-3-carboxypropyl)-S-butylsulfoximine
- NSC 381100
- Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)-.
- s-(3-amino-3-carboxypropyl)-s-butyl-sulfoximin
- butioninesulfoximine
- buthioninesulphoximine
- buthioninesulfoximine
- buthioninesulfoxamine
- 2-amino-4-(s-butylsulfonimidoyl)butanoicacid
- 2-amino-4-(s-butylsulfonimidoyl)-butanoicaci
- DL-BUTHIONINE-SULFOXIMINE
- DL-BUTHIONINE (S,R)-SULPHOXIME
- DL-BUTHIONINE-[S,R]-SULFOXIMINE
- DL-BUTHIONINE (R,S)-SULFOXIMINE