二氯尼特
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- CAS号:
- 579-38-4
- 英文名:
- diloxanide
- 英文别名:
- RD3803;RD 3803;RD-3803;Diloxanid;diloxanide;Diloxanida;diloxanide USP/EP/BP;α,α-Dichloro-4'-hydroxy-N-methylacetanilide;2,2-dichloro-N-(4-hydroxyphenyl)-N-methylacetamide;2,2-dichloro-N-(4-hydroxyphenyl)-N-methyl-acetamide
- 中文名:
- 二氯尼特
- 中文别名:
- 二氯尼特
- CBNumber:
- CB5875447
- 分子式:
- C9H9Cl2NO2
- 分子量:
- 234.08
- MOL File:
- 579-38-4.mol
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二氯尼特化学性质
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熔点:
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175°
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沸点:
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356.2±42.0 °C(Predicted)
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密度:
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1.439±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO:33.33(Max Conc. mg/mL);142.39(Max Conc. mM)
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酸度系数(pKa):
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9.95±0.15(Predicted)
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二氯尼特性质、用途与生产工艺
Diloxanide 是一种抗原虫制剂 (anti-protozoal agent)，可用于组织学内阿米巴原虫或者其他原虫感染引起的无症状肠道阿米巴病的研究。Diloxanide 是一种活性的鲁米那抗阿米巴试剂，在胃肠道中，由其前药二氯尼特糠酸酯 (HY-B1147) 水解得来。
Diloxanide is hydrolyzed in the gastrointestinal tract from its prodrug Diloxanide furoate.Diloxanide furoate (oral administraion; 75-200 mg/kg; 3 days; once daily) is effective at different dose of dayin weanling rats. At 200 mg/kg, 100% of the treated rats are cured and no amoebic lesions are observed in the caecum. Besides, 85%,77%, and 44.4% of the treated rats are cured at the dose 150 mg/kg, 100 mg/kg, and 75 mg/kg, respectively. The ED50 value is 77.9 mg/kg for this agent in rats.
二氯尼特
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-119972 | Diloxanide | | 1 mg | 142元 |
| 2024/01/25 | HY-119972 | Diloxanide | | 5 mg | 357元 |
579-38-4, 二氯尼特 相关搜索:
- 原料
- 二氯尼特
- 579-38-4
- infection,inhibit,Entamoeba histolytica,anti-protozoal,Parasite,amoebic colitis,Diloxanide,Inhibitor,luminal amebicide
- RD-3803
- RD3803
- RD 3803
- Diloxanida
- Diloxanid
- diloxanide USP/EP/BP
- Acetamide, 2,2-dichloro-N-(4-hydroxyphenyl)-N-methyl-
- 2,2-dichloro-N-(4-hydroxyphenyl)-N-methyl-ethanamide
- 2,2-dichloro-N-(4-hydroxyphenyl)-N-methyl-acetamide
- 2,2-dichloro-N-(4-hydroxyphenyl)-N-methylacetamide
- α,α-Dichloro-4'-hydroxy-N-methylacetanilide
- diloxanide