8-pCPT-2μ-O-Me-cAMP

634207-53-7

CAS-Nr.: 634207-53-7

Englisch Name:: 8-pCPT-2μ-O-Me-cAMP

Synonyma:: -O-Me-cAMP;8-pCPT-2’8-pCPT-2μ-O-Me-cAMP;8-pCPT-2'-O-Me-Cyclic AMP (sodium salt);8-(4-Chlorophenylthio)-2′-O-methyladenosine 3′,5′-cyclic monophosphate monosodium hydrate;8-(4-Chlorophenylthio)-2μ-O-methyladenosine 3μ,5μ-cyclic monophosphate hydrate monosodium

CBNumber:: CB02101804

Summenformel:: C17H16ClN5NaO6PS

Molgewicht:: 507.82

MOL-Datei:: 634207-53-7.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 25

8-pCPT-2μ-O-Me-cAMP Eigenschaften

Schmelzpunkt:: 235.5-237.5 °C(lit.)

storage temp.: −20°C

Löslichkeit: H2O: >10mg/mL

Aggregatzustand: solid

Farbe: white

Wasserlöslichkeit: Soluble to 100 mM in water

Sicherheit

S-Sätze:	22-24/25
WGK Germany	3

8-pCPT-2μ-O-Me-cAMP Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Verwenden

Exchange proteins activated by cAMP (Epacs) are guanine nucleotide exchange factors (GEFs) for the small GTPases Rap1 and Rap2. 8-pCPT-2'-O-Me-cAMP is a super-activator of Epacs in that it dissociates GDP from Rap1 more strongly than the natural Epac agonist, cAMP. 8-pCPT-2'-O-Me-cAMP is strongly selective for Epac over the cAMP-activated kinase PKA. It does not discriminate between Epac1 and Epac2 and is used extensively to elucidate the roles of these Rap GEFs in cell function.[Cayman Chemical]

Biochem/physiol Actions

Analog of natural cAMP, potent and specific membrane-permeant activator of exchange factors directly activated by cAMP (Epac or cAMP-GEF), a new receptor for cyclic AMP

8-pCPT-2μ-O-Me-cAMP Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

8-pCPT-2μ-O-Me-cAMP Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 25)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
BOC Sciences	+16314854226	inquiry@bocsci.com	United States	19743	58
NewCan Biotech Limited	+86-0571-86912261 +8613735419629	sales@newcanbio.com	China	10026	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
BOC Sciences	16314854226	inquiry@bocsci.com	United States	9713	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44941	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24131	58

8-pCPT-2'-O-Me-Cyclic AMP (sodium salt)
8-(4-Chlorophenylthio)-2μ-O-methyladenosine 3μ,5μ-cyclic monophosphate hydrate monosodium
8-pCPT-2μ-O-Me-cAMP
8-(4-Chlorophenylthio)-2′-O-methyladenosine 3′,5′-cyclic monophosphate monosodium hydrate
8-pCPT-2&rsquo
-O-Me-cAMP
634207-53-7
C17H16N5O6ClPSNa