8-pCPT-2μ-O-Me-cAMP

8-pCPT-2μ-O-Me-cAMP 구조식 이미지
카스 번호:
634207-53-7
상품명:
8-pCPT-2μ-O-Me-cAMP
동의어(영문):
-O-Me-cAMP;8-pCPT-2’8-pCPT-2μ-O-Me-cAMP;8-pCPT-2'-O-Me-Cyclic AMP (sodium salt);8-(4-Chlorophenylthio)-2′-O-methyladenosine 3′,5′-cyclic monophosphate monosodium hydrate;8-(4-Chlorophenylthio)-2μ-O-methyladenosine 3μ,5μ-cyclic monophosphate hydrate monosodium
CBNumber:
CB02101804
분자식:
C17H16ClN5NaO6PS
포뮬러 무게:
507.82
MOL 파일:
634207-53-7.mol
MSDS 파일:
SDS

8-pCPT-2μ-O-Me-cAMP 속성

녹는점
235.5-237.5 °C(lit.)
저장 조건
−20°C
용해도
H2O: >10mg/mL
물리적 상태
고체
물리적 상태
단단한 모양
색상
하얀색
수용성
물에 100mM까지 용해됨

안전

안전지침서 22-24/25
WGK 독일 3

8-pCPT-2μ-O-Me-cAMP C화학적 특성, 용도, 생산

용도

Exchange proteins activated by cAMP (Epacs) are guanine nucleotide exchange factors (GEFs) for the small GTPases Rap1 and Rap2. 8-pCPT-2'-O-Me-cAMP is a super-activator of Epacs in that it dissociates GDP from Rap1 more strongly than the natural Epac agonist, cAMP. 8-pCPT-2'-O-Me-cAMP is strongly selective for Epac over the cAMP-activated kinase PKA. It does not discriminate between Epac1 and Epac2 and is used extensively to elucidate the roles of these Rap GEFs in cell function.[Cayman Chemical]

Biochem/physiol Actions

Analog of natural cAMP, potent and specific membrane-permeant activator of exchange factors directly activated by cAMP (Epac or cAMP-GEF), a new receptor for cyclic AMP

8-pCPT-2μ-O-Me-cAMP 준비 용품 및 원자재

원자재

준비 용품


8-pCPT-2μ-O-Me-cAMP 공급 업체

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