RIMEXOLONE (100 MG)
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- CAS-Nr.
- 49697-38-3
- Englisch Name:
- RIMEXOLONE (100 MG)
- Synonyma:
- Vexol;Rimexel;Org-6216;Rimexolone;Rimexolone D6;Rimexolone D5;(11β,16α,17β)-;RIMEXOLONE (100 MG);Rimexolone (1604600);Benzoyl Peroxide Impurity 9
- CBNumber:
- CB0500540
- Summenformel:
- C24H34O3
- Molgewicht:
- 370.53
- MOL-Datei:
- 49697-38-3.mol
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RIMEXOLONE (100 MG) Eigenschaften
- Schmelzpunkt:
- 258-268 ºC
- alpha
- D +100° (c = 0.92 in pyridine)
- Siedepunkt:
- 507.0±50.0 °C(Predicted)
- Dichte
- 1.12
- pka
- 14.42±0.70(Predicted)
- InChIKey
- QTTRZHGPGKRAFB-OOKHYKNYSA-N
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H360 |
Kann die Fruchtbarkeit beeinträchtigen oder das Kind im Mutterleib schädigen. |
Fertility (Fruchtbarkeit) |
Kategorie 1 |
Achtung |
![GHS hazard pictograms]() src="/GHS08.jpg" width="20" height="20" /> |
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| Sicherheit |
| P201 |
Vor Gebrauch besondere Anweisungen einholen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P308+P313 |
BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen. |
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RIMEXOLONE (100 MG) Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Rimexolone, an ophthalmic corticosteroid, was launched in 1995 in the U.S.A. for
the treatment of postoperative inflammation following ocular surgery and anterior
uveitis. Rimexolone has high corticoid receptor affinity and is a potent local
antiinflammatory agent with minimal systemic effects and virtually no atrophogenic
action in many animal models studied, unique among a wide range of topical steroids.
Rapid onset, long duration of action plus a superior safety profile are characteristics of
rimexolone. It was also approved in Europe for the treatment of rheumatoid arthritis and
is currently in clinical trials for tendinitis and osteoarthritis.
Verwenden
Anti-inflammatory (local).
Allgemeine Beschreibung
Rimexolone, 11β-hydroxy-16α,17α-dimethyl-17-(1-oxopropyl)androsta-1,4-diene-3-one,like medrysone and fluorometholone, lacks the C21 OHgroup. In addition, rimexolone has an additional methylgroup in the 17 -position, a site where an OH group is typicallyfound. Rimexolone is available as a suspension forophthalmic use.
RIMEXOLONE (100 MG) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
RIMEXOLONE (100 MG) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 60)Lieferanten
- (11β,16α,17β)-
- (17S)-11β-Hydroxy-16α,17α-dimethyl-17-(1-oxopropyl)androsta-1,4-dien-3-one
- 11β-Hydroxy-16α,17α-dimethyl-17β-propionylandrosta-1,4-dien-3-one
- Org-6216
- (11b,16a,17b)-11-Hydroxy-16,17-dimethyl-17-(1-oxopropyl)androsta-1,4-dien-3-one
- RIMEXOLONE (100 MG)
- Rimexolone
- (11β, 16α, 17β)-11-Hydroxy-16,17-dimethyl-17-(1-oxopropyl)androstra-1,4-dien-3-one
- Androsta-1,4-dien-3-one, 11-hydroxy-16,17-dimethyl-17-(1-oxopropyl)-, (11β,16α,17β)-
- Rimexolone D5
- Rimexolone D6
- Rimexolone (1604600)
- Rimexel
- Vexol
- Methylprednisolone Impurity 31 (Rimexolone)
- Benzoyl Peroxide Impurity 9
- 49697-38-3
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Steroids
