Dantrolen Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Dantrolene acts as a skeletal muscle relaxant through inhibition of Ca2+ release through ryanodine receptor channels.
Definition
ChEBI: The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin.
Allgemeine Beschreibung
Crystals (in aqueous DMF).
Air & Water Reaktionen
Slightly water soluble. Dantrolene may be sensitive to heat and air .
Reaktivität anzeigen
A nitrated amine derivative. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Health Hazard
SYMPTOMS: When ingested, symptoms of exposure may include drowsiness, dizziness, weakness, general malaise, fatigue, diarrhea, constipation, gastrointestinal bleeding, anorexia, abdominal cramps, hepatitis, speech disturbance, seizure, headache, light-headedness, insomnia, tachycardia, phlebitis, mental depression, mental confusion, nervousness, abdominal hair growth, rash, sweating, backache, chills and fever.
Brandgefahr
Flash point data for Dantrolene are not available. Dantrolene is probably combustible.
Dantrolen Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
