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(5α,25R)-Spirostan-3β-ol

77-60-1

CAS-Nr.: 77-60-1

Bezeichnung:: (5α,25R)-Spirostan-3β-ol

Englisch Name:: Tigogenin

Synonyma:: Nsc93754;TIGOGENIN;Ticogenin;Sisalagenin;TIGOGENIN90%;Sisal saponin;Spirostan-3-ol;SMILAGENIN(RG);Trigonegenin B;Tsosarsasaprgein

CBNumber:: CB1669512

Summenformel:: C27H44O3

Molgewicht:: 416.64

MOL-Datei:: 77-60-1.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 219

(5α,25R)-Spirostan-3β-ol Eigenschaften

Schmelzpunkt:: 202-204°C

alpha: -68 º (c=0.8g/100ml, CHCl3)

Siedepunkt:: 474.91°C (rough estimate)

Dichte: 1.0362 (rough estimate)

Brechungsindex: 1.4700 (estimate)

storage temp.: -20°C Freezer, Under inert atmosphere

Löslichkeit: Chloroform (Slightly)

Aggregatzustand: Solid

pka: 15.14±0.70(Predicted)

Farbe: Off-White

CAS Datenbank: 77-60-1(CAS DataBase Reference)

NIST chemische Informationen: Tigogenin(77-60-1)

Sicherheit

RTECS-Nr.	WH1443500

(5α,25R)-Spirostan-3β-ol Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Tigogenin is a steroidal sapogenin that has been found in A. sisalana and has diverse biological activities. It increases the proliferation rate of, as well as mRNA levels of genes encoding the osteoblastic differentiation markers Cbfa1, collagen type I, and osteocalcin in, mouse bone marrow stromal cells (BMSCs) in a concentration-dependent manner. It also increases matrix calcium deposition in BMSCs when used at concentrations of 30 and 90 μM. Tigogenin is active against the fungus A. fumigatus (MIC₅₀ = 16 μg/ml). It inhibits carrageenan-induced paw edema in rats when administered at a dose of 4.2 μg/kg.

Chemische Eigenschaften

mp 196-208C° LOD ≤0.5%

Verwenden

Tigogenin is a saponin structurally similar to Diosgenin (D484700) and acts as a natural plant steroid which induces apoptosis in rheumatoid arthritic fibroblast-like synoviocytes.

(5α,25R)-Spirostan-3β-ol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Androst-3-ol-17-one 3-p-toluenesulfonate 3-Acetyloxy-16-methylpregna-9(11),16-dien-20-one 3-Acetyloxypregn-16-en-20-one 16-Methylpregnane-17,21-diol-3,20-dione 21-acetate 17-alpha-hydroxy-16-alpha-methyl-3,20-dioxopregna- 1,4-dien-21-yl acetate Oxymetholon 16,17-Epoxy-3-hydroxy-16-methyl-pregn-9(11)-ene-20-one-3-acetate 3β-Hydroxy-5α-pregna-9(11),16-dien-20-on-3-acetat

(5α,25R)-Spirostan-3β-ol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 219)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21689	55
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3424	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	sales@dolonchem.com	CHINA	2972	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Shanghai Standard Technology Co., Ltd.	18502101150	ft-sales@nature-standard.com	CHINA	1923	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58

77-60-1((5α,25R)-Spirostan-3β-ol)Verwandte Suche:

Ginseng extract Saponine (20R,25R)-Spirost-5-en-3β-ol 3-β-Hydroxy-5-α-spirostan-12-on TRIBULOSIDE Escin Ginsenoside Rh2 (25R)-5β-Spirostan-3β-ol Ginsenosides 12-Oxo-5-α-spirostan-3-β-ylacetat 2,15-Dihydroxyspirostan-3-yl-O-beta-D-glucopyrasonyl-(1-3)-O-D-galactopyranosyl-(1-2)O-(beta-D-xylo-pyranosyl-(1-3)-O-beta-D-glucopyranosyl-(1-4)-beta-D-galyctopyranosid, (2 alpha,3 beta, 5 alpha, 15 beta, 25R)- Escin sodium (25R)-5α-Spirostan-3β-ylacetat GSK-3 BETA (5α,25R)-Spirostan-3β-ol

TIGOGENIN
(25r)-5-alpha-spirostan-3-beta-o
25R,5ALPHA-SPIROSTAN-3BETA-OL
5-ALPHA, 20-ALPHA, 22-ALPHA, 25D-SPIROSTAN-3-BETA-OL
(25R)-5-Spirostan-3-ol
(3-beta,5-alpha,25r)-spirostan-3-o
5-alpha-spirostan-3-beta-ol
5alpha-Spirostan-3beta-ol, (25R)-
Spiro[8H-naphth[2',1':4,5]indeno[2,1-b]furan-8,2'-[2H]pyran], spirostan-3-ol deriv.
Spirostan-3-ol
Spirostan-3-ol, (3beta,5alpha,25R)-
Ticogenin
Tsosarsasaprgein
(5alpha,25R)-spirostan-3beta-ol
TIGOGENIN90%
SMILAGENIN(RG)
(3,5,25R)-3-Hydroxy-spirostane
(3-beta,5-alpha,25r)-spirostan-3-ol
TIGOGENIN (91%: 95%) (5A,25R)-SPIROSTAN-3B-OL)
Sisalagenin
(25R)-5a-Spirostan-3b-ol
(25R)-3β-Hydroxy-5α-spirostane
Trigonegenin B
Nsc93754
22-Isoallospirostan-3β-ol
(2aS,2'R,4S,5'R,6aS,6bS,8aS,8bR,9S,11aS,12aS,12bR)-5',6a,8a,9-TetraMethyldocosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-4-ol
22-Isoallospirostan-3β-ol
(25R)-5.α.-Spirostan-3.β.-ol
(2aS,4S,5'R,6aS,6bS,8aS,8bR,9S,10R,11aS,12aS,12bR)-5',6a,8a,9-Tetramethyldocosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-4-ol
5α, 20α, 22α, 25D-SPIROSTAN-3β-OL
Sisal saponin
(2aS,4S,5'R,6aS,6bS,8aS,8bR,9S,10R,11aS,12aS,12bR)-5',6a,8a,9-Tetramethyldocosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-4-ol
77-60-1
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