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Honokiol Produkt Beschreibung

Honokiol Struktur
35354-74-6
CAS-Nr.
35354-74-6
Englisch Name:
Honokiol
Synonyma:
hnk;houpa;HONOKIOL;NSC 293100;Honokiol>Honokiol,(S);Piclidenoson;Honokiol CRS;Honokiol 2%-98%;HonokiolStandard
CBNumber:
CB2111629
Summenformel:
C18H18O2
Molgewicht:
266.33
MOL-Datei:
35354-74-6.mol

Honokiol Eigenschaften

Schmelzpunkt:
86℃
Siedepunkt:
400.1±40.0 °C(Predicted)
Dichte
1.107±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
Löslichkeit
DMSO: 36 mg/mL
Aggregatzustand
powder
pka
9.89±0.48(Predicted)
Merck 
14,4742
InChIKey
FVYXIJYOAGAUQK-UHFFFAOYSA-N
CAS Datenbank
35354-74-6(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xi,N
R-Sätze: 41-51/53
S-Sätze: 26-39-61
RIDADR  UN 3077 9/PG 3
WGK Germany  3
HazardClass  9
HS Code  29072990
Bildanzeige (GHS)
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H318 Verursacht schwere Augenschäden. Schwere Augenschädigung Kategorie 1 Achtung P280, P305+P351+P338, P310
H401 Toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 2 P273, P501
H411 Giftig für Wasserorganismen, mit langfristiger Wirkung. Langfristig (chronisch) gewässergefährdend Kategorie 2
Sicherheit
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Honokiol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R41:Gefahr ernster Augenschäden.
R51/53:Giftig für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.

S-Sätze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S39:Schutzbrille/Gesichtsschutz tragen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.

Beschreibung

Magnolol is derived from the root bark and branch bark of magnolia or Magnolia officinalis. Magnolia officinalis was first written in the《ben jing》, it prefers cool and humid climate and well-drained acid soil. Cortex magnoliae officinalis (hou po) is mainly produced in Sichuan (Wan quan, Shizhu, Guanxian), Hubei (Shien,Yichang, Lichuan), Zhejiang (Longquan, Anhui), and other places. It is also distributed in Fujian, Jiangxi, Hunan, Guangxi, Yunnan, Guizhou, Shanxi, Gansu, and other places. Cortex magnoliae officinalis from Sichuan and Hubei is called “chuan pu,” with better quality, while in Zhejiang, it is called “warm park,” with a larger output.

Physikalische Eigenschaften

Appearance: white fine powder. Solubility: practically insoluble in water; very soluble in benzene, ethyl ether, chloroform, and acetone. Melting point: magnolol is 102 °C. Honokiol is 87.5 °C.

History

In 1930, magnolol was first isolated from the bark of Cortex magnoliae officinalis in China by Japanese Sugii, and it was also isolated from Cortex magnoliae officinalis in Japan. In 1973, magnolol and its isomers honokiol were isolated from Cortex magnoliae officinalis in China and Japan by Japanese Fujita.
The drug research and development of magnolol and honokiol remain in pharmacological activity and preclinical research. Kyung Hee University from Korea declared a preclinical study in 2003, in which allergy, anxiety, angina, and heart failure are indications for honokiol.

Verwenden

Honokiol is a small-molecule polyphenol isolated from the genus Magnolia. Recent studies show that Honokiol displays antiangiogenic, antiinflammatory, and antitumor properties in preclinical models, w ithout appreciable toxicity. Honokiol has been shown to inhibit the bone metastatic growth of human prostate cancer cells.

Indications

These compounds are recorded in the British Pharmacopoeia (2017) and European Pharmacopoeia (8.7th ed.). They are mainly used as antibacterial and antifungal agents.

Pharmakologie

Magnolol and honokiol have the pharmacological effects of prolonging central muscle relaxation, inhibition of the central nervous, anti-inflammatory, antibacterial, antimicrobial, antiulcer, antioxidant, antitumor, hormone regulation, and antidiabetes .

Honokiol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Honokiol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 360)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Shanghai Standard Technology Co., Ltd.
18502101150
+86-21-57127007-6606 ft-sales@nature-standard.com CHINA 1923 58
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 21032 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29961 58
Chengdu Biopurify Phytochemicals Ltd.
18482058008 18080483897
maggie@biopurify.com CHINA 2712 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28229 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282
sales3@crovellbio.com China 5361 58
Chongqing Chemdad Co.,Ltd
+86-19923101450
sales@chemdad.com CHINA 4000 58
Shaanxi Pioneer Biotech Co., Ltd .
86-13259417953(Whatsapp/Wechat) 86-13259417953(Whatsapp)
029-84385017 sales@pioneerbiotech.com CHINA 3001 58

35354-74-6()Verwandte Suche:


  • 5,3'-DIALLYL-BIPHENYL-2,4'-DIOL
  • HONOKIOL
  • 1’-Biphenyl]-2,4’-diol,3’,5-di-2-propenyl-[1
  • HONEYSUCKLEFLOWEREXTRACT
  • Honokiol,(S)
  • 3',5-Diallyl-2,4'-biphenyldiol
  • 3',5-Diallyl[1,1'-biphenyl]-2,4'-diol
  • 3,3'-DIALLYL-4,6'-DIHYDROXYBIPHENYL
  • HONOKIOL 98.0% BY HPLC
  • HonokiolStandard
  • 1'-Biphenyl]-2,4'-diol, 3',5-di-2- propenyl-[1-honokiol
  • [1,1'-Biphenyl]-2,4'-diol,3', 5-di-2-propenyl-
  • Nano Liposomal Honokiol
  • Honokiol, 98%, from Magnolia officinalis Rehder & E. H. Wilson
  • Magnolia officinalis extract
  • Honokiol 35354-74-6
  • Honokiol - CAS 35354-74-6 - Calbiochem
  • Honokiol, ≥98% (HPLC)
  • NSC 293100; NSC293100; NSC-293100
  • 4-phenyl-6,6-bis(prop-2-enyl)cyclohexa-1,3-diene-1,3-diol
  • Honokiol,5,3′-Diallyl-2,4′-dihydroxybiphenyl
  • 3',5-Diallyl-2,4'-dihydroxybiphenol
  • NSC 293100
  • Honokiol(NATURAL)
  • 3',5-di-2-propen-1-yl-[1,1'-biphenyl]-2,4'-diol
  • Honokiol, froM Houpoea officinalis
  • hnk
  • houpa
  • Piclidenoson
  • 2-(4-hydroxy-3-prop-2-enyl-phenyl)- 4-prop-2-enyl-phenol
  • 3',5-Diallyl-2,4'-dihydroxybiphenyl
  • 3',5-Diallylbiphenyl-2,4'-diol
  • 5,3'-DIALLYL-2,4'-DIHYDROXYBIPHENYL
  • 5,3'-DIALLYL-2,4'-DIHYDROXYDIPHENYL
  • Honokiol 2%-98%
  • Honokiol>
  • Honokiol CRS
  • [1,1'-Biphenyl]-2,4'-diol, 3',5-di-2-propen-1-yl-
  • 35354-74-6
  • C18H18O2
  • Antibiotics A to Z
  • Antibiotics
  • Antibiotics G-M
  • BioChemical
  • Inhibitors
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • natural product
  • Plant extract
  • Nutritional Ingredients
  • Antitumour
  • The group of Magnolia
  • Aromatic Phenols
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