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PICROTIN

PICROTIN Struktur
21416-53-5
CAS-Nr.
21416-53-5
Englisch Name:
PICROTIN
Synonyma:
PICROTIN;Picrotin CRS;(1aR,2aR,3S,6R,6aS,8aS,8bR,9S)-Hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-3,6-methano-8H-1,5,7-trioxacyclopenta[ij]cycloprop[a]azulene-4,8(3H)-dione;3,6-Methano-8H-1,5,7-trioxacyclopenta[ij]cycloprop[a]azulene-4,8(3H)-dione, hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-, (1aR,2aR,3S,6R,6aS,8aS,8bR,9S)-;(1aR,8aS,9S)-1aβ,2,2a,6,6aα,8b-Hexahydro-2aα-hydroxy-9-(1-hydroxy-1-methylethyl)-8bα-methyl-3α,6α-methano-8H-1,5,7-trioxacyclopenta[ij]cycloprop[a]azulene-4,8(3H)-dione
CBNumber:
CB2383778
Summenformel:
C15H18O7
Molgewicht:
310.3
MOL-Datei:
21416-53-5.mol
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PICROTIN Eigenschaften

Schmelzpunkt:
256-258°C
alpha 
D -64.7° (c = 2.31 in abs alc)
Siedepunkt:
595.8±50.0 °C(Predicted)
Dichte
1.59
storage temp. 
2-8°C
Löslichkeit
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2)(1:9): 0.1 mg/ml
pka
13.28±0.60(Predicted)
EPA chemische Informationen
Picrotin (21416-53-5)

Sicherheit

WGK Germany  3
RTECS-Nr. TJ8800000
Toxizität LD50 i.p. in mice: 135 mg/kg (Jarboe)

PICROTIN Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Picrotin is a natural picrotoxane that antagonizes glycine receptors (GlyRs; IC50s = 57 and 117 μM for α1 and α2 homodimeric GlyRs, respectively). It also inhibits α3 homodimeric GlyRs. Picrotin is inactive in inhibiting γ-aminobutyric acid (GABA) type A and type C receptors. Picrotin occurs in the natural plant-derived poison picrotoxin , equimolar with picrotoxinin.

Verwenden

GABAa receptor antagonist

PICROTIN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

PICROTIN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 69)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shanghai Zheyan Biotech Co., Ltd. 		18017610038
zheyansh@163.com CHINA 3620 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427
 sales@conier.com China 47465 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 19892 58
Aladdin Scientific 		+1-833-552-7181
sales@aladdinsci.com United States 57511 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006608290; 18621169109
 market03@meryer.com China 40241 62
Chengdu Climax Biotech Co., Ltd. 028-83311324 1278112614
climaxbiotech@gmail.com China 925 58
Shanghai Tauto Biotech Co., Ltd. 021-51320588
tauto@tautobiotech.com China 3989 66
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979
info@tsbiochem.com China 8073 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057
 3003855609@qq.com China 7893 56
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632
 sales@reading-chemicals.com China 15185 58

21416-53-5()Verwandte Suche:

(Tetrahydro-2-furyl)methylbutyrat α-Hydroxy-β,β-dimethyl-γ-butyrolacton Hexan-6-olid 3-Heptyldihydro-5-methylfuran-2(3H)-on Ethylheptyloxyacetat Pikrotoxin (±)-Dihydro-3-hydroxy-4,4-dimethylfuran-2(3H)-on Undecandisaeure [(Cyclohexyloxy)methyl]oxiran Dihydro-3-(3-methylbutyl)furan-2(3H)-on
  • PICROTIN
  • (1aR,8aS,9S)-1aβ,2,2a,6,6aα,8b-Hexahydro-2aα-hydroxy-9-(1-hydroxy-1-methylethyl)-8bα-methyl-3α,6α-methano-8H-1,5,7-trioxacyclopenta[ij]cycloprop[a]azulene-4,8(3H)-dione
  • (1aR,2aR,3S,6R,6aS,8aS,8bR,9S)-Hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-3,6-methano-8H-1,5,7-trioxacyclopenta[ij]cycloprop[a]azulene-4,8(3H)-dione
  • Picrotin CRS
  • 3,6-Methano-8H-1,5,7-trioxacyclopenta[ij]cycloprop[a]azulene-4,8(3H)-dione, hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-, (1aR,2aR,3S,6R,6aS,8aS,8bR,9S)-
  • 21416-53-5
  • C15H18O7
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