4'-CHLORO-3-METHOXYCINNAMANILIDE

472981-92-3

CAS-Nr.: 472981-92-3

Englisch Name:: 4'-CHLORO-3-METHOXYCINNAMANILIDE

Synonyma:: SB 366791;SB366791, >98%;SB 366791;SB366791;4'-CHLORO-3-METHOXYCINNAMANILIDE;4'-CHLORO-3-METHOXYCINNAMANILIDE;N-(3-METHOXYPHENYL)-4-CHLOROCINNAMIDE;4'-CHLORO-3-METHOXYCINNAMANILIDE(SB366791);(E)-3-(4-CHLOROPHENYL)-N-(3-METHOXYPHENYL)ACRYLAMIDE;3-(4-Chlorophenyl)-N-(3-methoxyphenyl)-2-propenamide;2-Propenamide,3-(4-chlorophenyl)-N-(3-methoxyphenyl)-

CBNumber:: CB2449409

Summenformel:: C16H14ClNO2

Molgewicht:: 287.74

MOL-Datei:: 472981-92-3.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 106

4'-CHLORO-3-METHOXYCINNAMANILIDE Eigenschaften

Schmelzpunkt:: 165-167℃

storage temp.: Sealed in dry,Room Temperature

Löslichkeit: DMSO: 13 mg/mL, soluble

Aggregatzustand: solid

Farbe: off-white

Stabilität:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Sicherheit

S-Sätze:	22-24/25
WGK Germany	3
HS Code	2924.29.7790

4'-CHLORO-3-METHOXYCINNAMANILIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Verwenden

N-(4-Methoxyphenyl)-4-chlorocinnamamide is a novel, potent, and selective cinnamide TRPV1 antagonist. Also a useful tool to further study the biology of TRPV1.

Biologische Aktivität

Potent, selective and competitive vanilloid TRPV1 (VR1) receptor antagonist (pA 2 = 7.71 at hVR1); antagonizes hTRPV1 receptors activated by agonists, noxious heat, but not protons. Displays selectivity over a wide range of receptors and systems including CB 1 and CB 2 receptors, voltage-gated Ca 2+ channels and the hyperpolarization-activated current (I h ). Also available as part of the Vanilloid TRPV1 Receptor Tocriset™ .

Biochem/physiol Actions

SB-366791 might exhibit analgesic properties on bone cancer-related pain behavior.

4'-CHLORO-3-METHOXYCINNAMANILIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

4'-CHLORO-3-METHOXYCINNAMANILIDE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 106)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5738	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Hunan Hui Bai Shi Biotechnology Co., Ltd.	0731-85526065 13308475853	ivy@hnhbsj.com	China	4550	62

N-(3-METHOXYPHENYL)-4-CHLOROCINNAMIDE
SB 366791
4'-CHLORO-3-METHOXYCINNAMANILIDE
3-(4-Chlorophenyl)-N-(3-methoxyphenyl)-2-propenamide
(E)-3-(4-CHLOROPHENYL)-N-(3-METHOXYPHENYL)ACRYLAMIDE
2-Propenamide,3-(4-chlorophenyl)-N-(3-methoxyphenyl)-
SB 366791;SB366791
SB366791, >98%
4'-CHLORO-3-METHOXYCINNAMANILIDE(SB366791)
4'-CHLORO-3-METHOXYCINNAMANILIDE
472981-92-3
C16H14NO2Cl
Vanilloid/TRPV channel
API