HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS

29400-42-8

CAS-Nr.: 29400-42-8

Englisch Name:: HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS

Synonyma:: fumigacin;Helvolic acid (Fumigacin);HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS;6-beta,8-alpha,9-beta,13-alpha,14-beta,16-beta,17-beta)--alph;17(20),24-trien-21-oicacid,6,16-bis(acetyloxy)-3,7-dioxo-29-nordammara-(4;(8α,9β,13α,14β,17Z)-6β,16β-Diacetoxy-3,7-dioxo-29-nor-5α-dammara-1,17(20),24-trien-21-oic acid;(8α,9β,13α,14β,17Z)-6β,16β-Bis(acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid;(4α,8α,9β,13α,14β,17Z)-6β,16β-Bis(acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid;29-Nordammara-1,17(20),24-trien-21-oic acid, 6,16-bis(acetyloxy)-3,7-dioxo-, (4α,6β,8α,9β,13α,14β,16β,17Z)-

CBNumber:: CB2503570

Summenformel:: C33H44O8

Molgewicht:: 568.7

MOL-Datei:: 29400-42-8.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 26

HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS Eigenschaften

Schmelzpunkt:: 215°

alpha: D25 -121° (chloroform)

Siedepunkt:: 552.56°C (rough estimate)

Dichte: 1.1062 (rough estimate)

Brechungsindex: 1.4900 (estimate)

storage temp.: 2-8°C

Löslichkeit: DMF:30.0(Max Conc. mg/mL);52.75(Max Conc. mM)
DMSO:20.0(Max Conc. mg/mL);35.17(Max Conc. mM)
Ethanol:20.0(Max Conc. mg/mL);35.17(Max Conc. mM)

Aggregatzustand: A crystalline solid

pka: 4.05±0.41(Predicted)

Sicherheit

RTECS-Nr.	RC1370000
HS Code	29419000

HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Helvolic acid is a mycotoxin originally isolated from A. fumigatus that has broad-spectrum antibiotic activity against Gram-positive and Gram-negative bacteria. At 4-16 mg/L, it acted synergistically with erythromycin (500-2,000 mg/L) in vitro on five multi-drug resistant strains of S. aureus. At 10 mg/kg/d, it reduced tumor growth and prolonged survival synergistically with cyclophosphamide (20 mg/kg/d) in a mouse model of sarcoma but had no effect when administered alone.

Verwenden

Helvolic acid is a mycotoxin with antibacterial activity.

Definition

ChEBI: A steroid C-21 acid having a 29-nordammarane skeleton substituted with an acetoxy group at C-16 and oxo groups at C-3 and -7, with double bonds at C-1, -17(20) and -24.

HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 26)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
BOC Sciences	+16314854226	inquiry@bocsci.com	United States	19743	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Lynnchem	86-(0)29-85992781 17792393971	info@lynnchem.com	China	4587	58
Novachemistry	44-20819178-90 02081917890	info@novachemistry.com	United Kingdom	4381	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Chengdu Jiuding Chemical Technology Co., Ltd. - Song Bo	18584079237	312074905@qq.com	China	2507	58

29400-42-8()Verwandte Suche:

3,5,5-Trimethylhexylformiat 4-Methyl-3-decen-5-ol Geranylacetat (E)-2-Methylpent-2-en-1-sure But-2-en-1,4-diol Oct-2-ensure cis-Octahydronaphthalin-2(1H)-on 2,6,10-Trimethylundec-9-enal Ethylidencyclopentan 5-Hydroxyoctan-4-on 3,3,5,5-Tetramethylcyclohexanol 7-Hydroxydodecan-6-on 2-Propylhept-2-enal cis-3,3,5-Trimethylcyclohexylacetat 4-Hydroxydecan-5-on

17(20),24-trien-21-oicacid,6,16-bis(acetyloxy)-3,7-dioxo-29-nordammara-(4
6-beta,8-alpha,9-beta,13-alpha,14-beta,16-beta,17-beta)--alph
fumigacin
HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS
(4α,8α,9β,13α,14β,17Z)-6β,16β-Bis(acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid
(8α,9β,13α,14β,17Z)-6β,16β-Bis(acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid
(8α,9β,13α,14β,17Z)-6β,16β-Diacetoxy-3,7-dioxo-29-nor-5α-dammara-1,17(20),24-trien-21-oic acid
29-Nordammara-1,17(20),24-trien-21-oic acid, 6,16-bis(acetyloxy)-3,7-dioxo-, (4α,6β,8α,9β,13α,14β,16β,17Z)-
Helvolic acid (Fumigacin)
29400-42-8
C33H44O8