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HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS
- CAS No.
- 29400-42-8
- Chemical Name:
- HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS
- Synonyms
- fumigacin;Helvolic acid (Fumigacin);HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS;6-beta,8-alpha,9-beta,13-alpha,14-beta,16-beta,17-beta)--alph;17(20),24-trien-21-oicacid,6,16-bis(acetyloxy)-3,7-dioxo-29-nordammara-(4;(8α,9β,13α,14β,17Z)-6β,16β-Diacetoxy-3,7-dioxo-29-nor-5α-dammara-1,17(20),24-trien-21-oic acid;(8α,9β,13α,14β,17Z)-6β,16β-Bis(acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid;(4α,8α,9β,13α,14β,17Z)-6β,16β-Bis(acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid;29-Nordammara-1,17(20),24-trien-21-oic acid, 6,16-bis(acetyloxy)-3,7-dioxo-, (4α,6β,8α,9β,13α,14β,16β,17Z)-
- CBNumber:
- CB2503570
- Molecular Formula:
- C33H44O8
- Molecular Weight:
- 568.7
- MDL Number:
- MFCD32689348
- MOL File:
- 29400-42-8.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:12
| Melting point | 215° |
|---|---|
| alpha | D25 -121° (chloroform) |
| Boiling point | 552.56°C (rough estimate) |
| Density | 1.1062 (rough estimate) |
| refractive index | 1.4900 (estimate) |
| storage temp. | 2-8°C |
| solubility |
DMF:30.0(Max Conc. mg/mL);52.75(Max Conc. mM) DMSO:20.0(Max Conc. mg/mL);35.17(Max Conc. mM) Ethanol:20.0(Max Conc. mg/mL);35.17(Max Conc. mM) |
| form | A crystalline solid |
| pka | 4.05±0.41(Predicted) |
| FDA UNII | MZX54GS8AH |
HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 21580 | Helvolic Acid ≥98% | 29400-42-8 | 1mg | $72 | 2024-03-01 | Buy |
| Cayman Chemical | 21580 | Helvolic Acid ≥98% | 29400-42-8 | 5mg | $231 | 2024-03-01 | Buy |
| TRC | H235125 | HelvolicAcid | 29400-42-8 | 50mg | $3090 | 2021-12-16 | Buy |
| Apolloscientific | BIBR1050 | Helvolicacid | 29400-42-8 | 5mg | $435 | 2021-12-16 | Buy |
| Apolloscientific | BIBR1050 | Helvolicacid | 29400-42-8 | 1mg | $109 | 2021-12-16 | Buy |
HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS Chemical Properties,Uses,Production
Description
Helvolic acid is a mycotoxin originally isolated from A. fumigatus that has broad-spectrum antibiotic activity against Gram-positive and Gram-negative bacteria. At 4-16 mg/L, it acted synergistically with erythromycin (500-2,000 mg/L) in vitro on five multi-drug resistant strains of S. aureus. At 10 mg/kg/d, it reduced tumor growth and prolonged survival synergistically with cyclophosphamide (20 mg/kg/d) in a mouse model of sarcoma but had no effect when administered alone.
Uses
Helvolic acid is a mycotoxin with antibacterial activity.
Definition
ChEBI: A steroid C-21 acid having a 29-nordammarane skeleton substituted with an acetoxy group at C-16 and oxo groups at C-3 and -7, with double bonds at C-1, -17(20) and -24.
HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS Preparation Products And Raw materials
Raw materials
Preparation Products
HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS Suppliers
Global( 26)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| BOC Sciences | +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4587 | 58 |
| Novachemistry | 44-20819178-90 02081917890 | info@novachemistry.com | United Kingdom | 4381 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Chengdu Jiuding Chemical Technology Co., Ltd. - Song Bo | 18584079237 | 312074905@qq.com | China | 2507 | 58 |
29400-42-8(HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS)Related Search:
17(20),24-trien-21-oicacid,6,16-bis(acetyloxy)-3,7-dioxo-29-nordammara-(4
6-beta,8-alpha,9-beta,13-alpha,14-beta,16-beta,17-beta)--alph
fumigacin
HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS
(4α,8α,9β,13α,14β,17Z)-6β,16β-Bis(acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid
(8α,9β,13α,14β,17Z)-6β,16β-Bis(acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid
(8α,9β,13α,14β,17Z)-6β,16β-Diacetoxy-3,7-dioxo-29-nor-5α-dammara-1,17(20),24-trien-21-oic acid
29-Nordammara-1,17(20),24-trien-21-oic acid, 6,16-bis(acetyloxy)-3,7-dioxo-, (4α,6β,8α,9β,13α,14β,16β,17Z)-
Helvolic acid (Fumigacin)
29400-42-8
C33H44O8