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DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2

DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2 Struktur
133156-06-6
CAS-Nr.
133156-06-6
Englisch Name:
DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2
Synonyma:
GR 73632;GR-73632 (GR73632);H2H-(CH2)4-CO-PHE-PRO-NME-LEU-MET-NH2;d-AMinovaleryl-Phe-Phe-Pro-N-Me-Leu-Met-NH2;DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2;d-AMinovaleryl-(Pro9,N-Me-Leu10)-Substance P (7-11);δ-Aminovaleryl-(Pro9,N-Me-Leu10)-Substance P (7-11);DELTA-AMINOVALERYL-(PRO9,N-ME-LEU10)-SUBSTANCE P (7-11);(DELTA-AMINOVALERYL6,PRO9,N-ME-LEU10)-SUBSTANCE P (6-11);δ-Aminovaleryl-[Pro9, Leu(N-Me)10]-SubstanceP Fragment 7-11
CBNumber:
CB3126730
Summenformel:
C40H59N7O6S
Molgewicht:
766
MOL-Datei:
133156-06-6.mol
Request For Quotation

DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2 Eigenschaften

Siedepunkt:
1082.2±65.0 °C(Predicted)
Dichte
1.198±0.06 g/cm3(Predicted)
storage temp. 
-20°C
Löslichkeit
Water:1.0(Max Conc. mg/mL);1.31(Max Conc. mM)
Aggregatzustand
Powder
pka
13.34±0.46(Predicted)
Wasserlöslichkeit
Soluble to 1 mg/ml in water

Sicherheit

S-Sätze: 22-24/25
WGK Germany  3

DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2 Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Verwenden

GR 73632 is a NK1 tachykinin receptor agonist used in the treatment of asthma and gastrointestinal disorders. It is involved in the contraction of muscles.

Allgemeine Beschreibung

Neurokinin (NK) receptors are acted upon by tachykinins or neurokinins namely, NKA and NKB. These are endogenous ligands. An exogenous agonist/ligand for NK1 is GR 64349 petpide.

Biochem/physiol Actions

GR 73632 interacts with neurokinin (NK1) receptor, which results in rhythmic tapping of hind-foot in gerbils. Administration of this peptide in the intra-ventral tegmental area (VTA) results in locomotor activity. It interacts with and activates NK1 receptors present on smooth muscle and interstitial cells of Cajal, resulting in elevated distention-induced peristalsis.

DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 50)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Career Henan Chemica Co 		+86-0371-86658258 15093356674;
 laboratory@coreychem.com China 30255 58
BOC Sciences 		+16314854226
 inquiry@bocsci.com United States 19743 58
Chengdu Youngshe Chemical Co., Ltd. 		+8618108235634
 Cecilia@youngshechem.com China 2345 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131981 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15848 69
Chemsky（shanghai）International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32344 50
Sigma-Aldrich 021-61415566 800-8193336
 orderCN@merckgroup.com China 51471 80
Nanjing Leon Biological Technology Co., Ltd. 17705183659
 sales@njleonbiotech.com China 5503 55
Nanjing Peptide Biotech Ltd. 025-58361106-805 13082558573
 liugang@njpeptide.com China 9961 55
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919
eric@peptidego.com China 6347 58
  • δ-Aminovaleryl-[Pro9, Leu(N-Me)10]-SubstanceP Fragment 7-11
  • N-(5-Amino-1-oxopentyl)-L-Phe-L-Phe-L-Pro-N-methyl-L-Leu-L-Met-NH2
  • (2S)-1-[(2S)-2-[[(2S)-2-(5-aminopentanoylamino)-3-phenyl-propanoyl]amino]-3-phenyl-propanoyl]-N-[(1S)-1-[[(1S)-1-carbamoyl-3-(methylthio)propyl]carbamoyl]-3-methyl-butyl]-N-methyl-pyrrolidine-2-carboxamide
  • (2S)-N-[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-[(2S)-2-[[(2S)-2-(5-aminopentanoylamino)-3-phenylpropanoyl]amino]-3-phenylpropanoyl]-N-methylpyrrolidine-2-carboxamide
  • (2S)-N-[(2S)-1-[[(2S)-1-azanyl-4-methylsulfanyl-1-oxo-butan-2-yl]amino]-4-methyl-1-oxo-pentan-2-yl]-1-[(2S)-2-[[(2S)-2-(5-azanylpentanoylamino)-3-phenyl-propanoyl]amino]-3-phenyl-propanoyl]-N-methyl-pyrrolidine-2-carboxamide
  • d-AMinovaleryl-(Pro9,N-Me-Leu10)-Substance P (7-11)
  • d-AMinovaleryl-Phe-Phe-Pro-N-Me-Leu-Met-NH2
  • GR 73632
  • H2H-(CH2)4-CO-PHE-PRO-NME-LEU-MET-NH2
  • (DELTA-AMINOVALERYL6,PRO9,N-ME-LEU10)-SUBSTANCE P (6-11)
  • DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2
  • DELTA-AMINOVALERYL-(PRO9,N-ME-LEU10)-SUBSTANCE P (7-11)
  • L-Methioninamide,N-(5-amino-1-oxopentyl)-L-phenylalanyl-L-phenylalanyl-L-prolyl-N-methyl-L-leucyl-
  • GR-73632 (GR73632)
  • δ-Aminovaleryl-(Pro9,N-Me-Leu10)-Substance P (7-11)
  • Neurokinin Receptor,NK receptor,Tachykinin receptor,GR73632,inhibit,Inhibitor,GR-73632,GR 73632
  • 133156-06-6
  • C40H59N7O6S
  • Peptides
  • Tachykinins
  • Biochemicals and Reagents
  • Agonist
  • Amino Acids and Peptides
  • BioChemical
  • AgonistPeptides for Cell Biology
  • Neuropeptides
  • Peptides for Cell Biology
  • Tachykinins
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