DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2

DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2 구조식 이미지
카스 번호:
133156-06-6
상품명:
DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2
동의어(영문):
GR 73632;GR-73632 (GR73632);H2H-(CH2)4-CO-PHE-PRO-NME-LEU-MET-NH2;d-AMinovaleryl-Phe-Phe-Pro-N-Me-Leu-Met-NH2;DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2;d-AMinovaleryl-(Pro9,N-Me-Leu10)-Substance P (7-11);δ-Aminovaleryl-(Pro9,N-Me-Leu10)-Substance P (7-11);DELTA-AMINOVALERYL-(PRO9,N-ME-LEU10)-SUBSTANCE P (7-11);(DELTA-AMINOVALERYL6,PRO9,N-ME-LEU10)-SUBSTANCE P (6-11);δ-Aminovaleryl-[Pro9, Leu(N-Me)10]-SubstanceP Fragment 7-11
CBNumber:
CB3126730
분자식:
C40H59N7O6S
포뮬러 무게:
766
MOL 파일:
133156-06-6.mol

DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2 속성

끓는 점
1082.2±65.0 °C(Predicted)
밀도
1.198±0.06 g/cm3(Predicted)
저장 조건
-20°C
용해도
Water:1.0(Max Conc. mg/mL);1.31(Max Conc. mM)
물리적 상태
가루
산도 계수 (pKa)
13.34±0.46(Predicted)
수용성
Soluble to 1 mg/ml in water

안전

안전지침서 22-24/25
WGK 독일 3

DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2 C화학적 특성, 용도, 생산

용도

GR 73632 is a NK1 tachykinin receptor agonist used in the treatment of asthma and gastrointestinal disorders. It is involved in the contraction of muscles.

일반 설명

Neurokinin (NK) receptors are acted upon by tachykinins or neurokinins namely, NKA and NKB. These are endogenous ligands. An exogenous agonist/ligand for NK1 is GR 64349 petpide.

Biochem/physiol Actions

GR 73632 interacts with neurokinin (NK1) receptor, which results in rhythmic tapping of hind-foot in gerbils. Administration of this peptide in the intra-ventral tegmental area (VTA) results in locomotor activity. It interacts with and activates NK1 receptors present on smooth muscle and interstitial cells of Cajal, resulting in elevated distention-induced peristalsis.

DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2 준비 용품 및 원자재

원자재

준비 용품


DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2 공급 업체

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