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(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Struktur
56715-13-0
CAS-Nr.
56715-13-0
Englisch Name:
(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE
Synonyma:
(+)-Atenolol;(R)-(+)-ATENOLOL;Atenolol R-Isomer;(R)-(+)-AtenololHCl;(R)-(+)-Atenolol 99%;R(+)-ATENOLOL LESS ACTIVE ENANTIOME;Atenolol Impurity 15 ((R)-Atenolol);(R)-2-(4-(2-hydroxy-3-(isopropylaMino)propoxy)phenyl)acetaMide;2-[4-[(2R)-2-hydroxy-3-(isopropylamino)propoxy]phenyl]acetamide;4-[(R)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide
CBNumber:
CB4230500
Summenformel:
C14H22N2O3
Molgewicht:
266.34
MOL-Datei:
56715-13-0.mol
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(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Eigenschaften

Schmelzpunkt:
148-152 °C(lit.)
Siedepunkt:
508.0±50.0 °C(Predicted)
Dichte
1.125±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
Löslichkeit
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: >6.0 mg/mL
pka
13.88±0.20(Predicted)
Aggregatzustand
solid
Farbe
pale yellow
Optische Aktivität
[α]25/D +16°, c = 1 in 1 M HCl

Sicherheit

WGK Germany  3

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

(+)-Atenolol is an enantiomer of the β1-adrenergic receptor (β1-AR) antagonist (±)-atenolol . (+)-Atenolol inhibits radioligand binding to β-ARs on sarcolemma-enriched membranes (Ki = 8.61 μM). Unlike (–)-atenolol and (±)-antenolol, (+)-atenolol has no effect on blood pressure in spontaneously hypertensive rats.

Verwenden

Cardioselective β-adrenergic blocker. Antihypertensive, antianginal, antiarrhythmic (class II).

Definition

ChEBI: The (R)-enantiomer of atenolol.

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Atenolol S(-)-ATENOLOL 4-Hydroxyphenylacetamid p-Hydroxyphenylessigsure Isopropylamin

Downstream Produkte

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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56715-13-0()Verwandte Suche:

4-Hydroxyphenylacetamid Atenolol 3-(Isopropylamino)propan-1,2-diol
  • 4-[(R)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide
  • 2-[4-[(2R)-2-hydroxy-3-(isopropylamino)propoxy]phenyl]acetamide
  • 2-[4-[(2R)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide
  • 2-[4-[(2R)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]ethanamide
  • (R)-(+)-Atenolol,(+)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide
  • R(+)-ATENOLOL LESS ACTIVE ENANTIOME
  • Benzeneacetamide, 4-[(2R)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]-
  • Benzeneacetamide, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-, (R)-
  • 4-[(2R)-2-Hydroxy-3-[(1-Methylethyl)aMino]propoxy]benzeneacetaMide
  • (R)-2-(4-(2-hydroxy-3-(isopropylaMino)propoxy)phenyl)acetaMide
  • Atenolol R-Isomer
  • (R)-(+)-Atenolol 99%
  • (R)-(+)-ATENOLOL
  • (R)-(+)-AtenololHCl
  • (+)-2-[4-[(2R)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy] phenyl] acetamide
  • (+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE
  • (+)-Atenolol
  • Atenolol Impurity 15 ((R)-Atenolol)
  • Prenormin,2-[4-[(2R)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide
  • 56715-13-0
  • CH32CHNHCH2CHOHCH2OC6H4CH2CONH2
  • Amino Alcohols
  • Chiral Building Blocks
  • Asymmetric Synthesis
  • Organic Building Blocks
  • Amines
  • Aromatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
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