(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE 구조식 이미지
카스 번호:
56715-13-0
상품명:
(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE
동의어(영문):
(+)-Atenolol;(R)-(+)-ATENOLOL;Atenolol R-Isomer;(R)-(+)-AtenololHCl;(R)-(+)-Atenolol 99%;R(+)-ATENOLOL LESS ACTIVE ENANTIOME;Atenolol Impurity 15 ((R)-Atenolol);(R)-2-(4-(2-hydroxy-3-(isopropylaMino)propoxy)phenyl)acetaMide;2-[4-[(2R)-2-hydroxy-3-(isopropylamino)propoxy]phenyl]acetamide;4-[(R)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide
CBNumber:
CB4230500
분자식:
C14H22N2O3
포뮬러 무게:
266.34
MOL 파일:
56715-13-0.mol

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE 속성

녹는점
148-152 °C(lit.)
끓는 점
508.0±50.0 °C(Predicted)
밀도
1.125±0.06 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
45% (w/v) aq 2-히드록시프로필-β-시클로덱스트린: >6.0 mg/mL
산도 계수 (pKa)
13.88±0.20(Predicted)
물리적 상태
고체
물리적 상태
단단한 모양
색상
옅은 노랑
optical activity
[α]25/D +16°, c = 1 in 1 M HCl

안전

WGK 독일 3

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE C화학적 특성, 용도, 생산

개요

(+)-Atenolol is an enantiomer of the β1-adrenergic receptor (β1-AR) antagonist (±)-atenolol . (+)-Atenolol inhibits radioligand binding to β-ARs on sarcolemma-enriched membranes (Ki = 8.61 μM). Unlike (–)-atenolol and (±)-antenolol, (+)-atenolol has no effect on blood pressure in spontaneously hypertensive rats.

용도

Cardioselective β-adrenergic blocker. Antihypertensive, antianginal, antiarrhythmic (class II).

정의

ChEBI: The (R)-enantiomer of atenolol.

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE 준비 용품 및 원자재

원자재

준비 용품


(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE 공급 업체

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