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ChemicalBook >> CAS DataBase List >>(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Structure
(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE structure
CAS No.
56715-13-0
Chemical Name:
(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE
Synonyms
(+)-Atenolol;(R)-(+)-ATENOLOL;Atenolol R-Isomer;(R)-(+)-AtenololHCl;(R)-(+)-Atenolol 99%;R(+)-ATENOLOL LESS ACTIVE ENANTIOME;Atenolol Impurity 15 ((R)-Atenolol);(R)-2-(4-(2-hydroxy-3-(isopropylaMino)propoxy)phenyl)acetaMide;2-[4-[(2R)-2-hydroxy-3-(isopropylamino)propoxy]phenyl]acetamide;4-[(R)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide
CBNumber:
CB4230500
Molecular Formula:
C14H22N2O3
Molecular Weight:
266.34
MDL Number:
MFCD00074917
MOL File:
56715-13-0.mol
Last updated:2023-05-21 10:59:17
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(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Properties

Melting point 148-152 °C(lit.)
Boiling point 508.0±50.0 °C(Predicted)
Density 1.125±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: >6.0 mg/mL
pka 13.88±0.20(Predicted)
form solid
color pale yellow
optical activity [α]25/D +16°, c = 1 in 1 M HCl
FDA UNII YG132I00WY

SAFETY

Risk and Safety Statements

WGK Germany  3

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 330884 (R)-(+)-Atenolol 99% 56715-13-0 100mg $160 2024-03-01 Buy
Cayman Chemical 18623 (R)-(+)-Atenolol ≥98% 56715-13-0 1mg $32 2024-03-01 Buy
Cayman Chemical 18623 (R)-(+)-Atenolol ≥98% 56715-13-0 5mg $139 2024-03-01 Buy
Cayman Chemical 18623 (R)-(+)-Atenolol ≥98% 56715-13-0 10mg $243 2024-03-01 Buy
Cayman Chemical 18623 (R)-(+)-Atenolol ≥98% 56715-13-0 25mg $533 2024-03-01 Buy
Product number Packaging Price Buy
330884 100mg $160 Buy
18623 1mg $32 Buy
18623 5mg $139 Buy
18623 10mg $243 Buy
18623 25mg $533 Buy

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Chemical Properties,Uses,Production

Description

(+)-Atenolol is an enantiomer of the β1-adrenergic receptor (β1-AR) antagonist (±)-atenolol . (+)-Atenolol inhibits radioligand binding to β-ARs on sarcolemma-enriched membranes (Ki = 8.61 μM). Unlike (–)-atenolol and (±)-antenolol, (+)-atenolol has no effect on blood pressure in spontaneously hypertensive rats.

Uses

less active enantiomer

Uses

Antihypertensor

Uses

Cardioselective β-adrenergic blocker. Antihypertensive, antianginal, antiarrhythmic (class II).

Definition

ChEBI: The (R)-enantiomer of atenolol.

References

[1] stoschitzky k, egginger g, zernig g, et al. stereoselective features of (r)- and (s)-atenolol: clinical pharmacological, pharmacokinetic, and radioligand binding studies[j]. chirality, 1993, 5(1): 15-19.

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Preparation Products And Raw materials

Raw materials

Atenolol S(-)-ATENOLOL 4-Hydroxyphenylacetamide 4-Hydroxyphenylacetic acid Isopropylamine

Preparation Products

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Suppliers

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sgtlifesciences pvt ltd 		58
Alfa Chemistry 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
China National Standard Pharmaceutical Corporation Limited 		58
Aladdin Scientific 		58
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Energy Chemical 61
Chemsky (shanghai) International Co.,Ltd 60
Syntechem Co.,Ltd 57

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Spectrum

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE(56715-13-0)1HNMR(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE(56715-13-0)Raman(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE(56715-13-0)IR(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE(56715-13-0)FT-IR

56715-13-0((+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE)Related Search:

S(-)-ATENOLOL (+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Atenolol 4-Hydroxyphenylacetamide 4-METHOXYPHENYLACETAMIDE
1-AMINO-3-PHENOXY-PROPAN-2-OL 3-(4-methylphenoxy)propan-1-amine CHEMBRDG-BB 5482082 (2R)-(+)-1-AMINO-3-PHENOXY-2-PROPANOL AKOS BC-1949
4-(3-Amino-2-hydroxypropoxy)phenylacetamide 3-(ISOPROPYLAMINO)-1,2-PROPANEDIOL 1-AMINO-3-(4-ETHYLPHENOXY)PROPAN-2-OL (R)-3-ISOPROPYLAMINO-1,2-PROPANEDIOL 1-METHYLAMINO-3-PHENOXY-PROPAN-2-OL
CHEMBRDG-BB 9070877 ATENOLOL IMPURITY STANDARD

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4-[(R)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide 2-[4-[(2R)-2-hydroxy-3-(isopropylamino)propoxy]phenyl]acetamide 2-[4-[(2R)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide 2-[4-[(2R)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]ethanamide (R)-(+)-Atenolol,(+)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide R(+)-ATENOLOL LESS ACTIVE ENANTIOME Benzeneacetamide, 4-[(2R)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]- Benzeneacetamide, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-, (R)- 4-[(2R)-2-Hydroxy-3-[(1-Methylethyl)aMino]propoxy]benzeneacetaMide (R)-2-(4-(2-hydroxy-3-(isopropylaMino)propoxy)phenyl)acetaMide Atenolol R-Isomer (R)-(+)-Atenolol 99% (R)-(+)-ATENOLOL (R)-(+)-AtenololHCl (+)-2-[4-[(2R)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy] phenyl] acetamide (+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE (+)-Atenolol Atenolol Impurity 15 ((R)-Atenolol) Prenormin,2-[4-[(2R)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide 56715-13-0 CH32CHNHCH2CHOHCH2OC6H4CH2CONH2 Amino Alcohols Chiral Building Blocks Asymmetric Synthesis Organic Building Blocks Amines Aromatics Intermediates & Fine Chemicals Pharmaceuticals