CGP 35348

123690-79-9

CAS-Nr.: 123690-79-9

Englisch Name:: CGP 35348

Synonyma:: CGP 35348;CGP 35348 hydrate;(3-AMINOPROPYL)(DIETHOXYMETHYL)PHOSPHINIC ACID;Phosphinic acid, (3-aminopropyl)(diethoxymethyl)-;P-(3-Aminopropyl)-P-(diethoxymethyl)phosphinic acid;Phosphinic acid, P-(3-aminopropyl)-P-(diethoxymethyl)-;(3-Aminopropyl)(diethoxymethyl)phosphinic acid hydrate;spatial learning,neuromuscular,neonatal damage,CGP-35348,brain penetrant,GABA Receptor,CGP35348,Gamma-aminobutyric acid Receptor,centrally,GABAB,CGP 35348,Inhibitor,γ-Aminobutyric acid Receptor,inhibit,active

CBNumber:: CB4386728

Summenformel:: C8H20NO4P

Molgewicht:: 225.22

MOL-Datei:: 123690-79-9.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 38

CGP 35348 Eigenschaften

storage temp.: −20°C

Löslichkeit: H₂O: >10 mg/mL

Aggregatzustand: solid

Farbe: white

Wasserlöslichkeit: Soluble in water (100mM)

Sicherheit

WGK Germany	3

CGP 35348 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

CGP 35348 hydrate has been used as a γ-aminobutyric acid-B (GABA_B) receptor inhibitor:

to study its effects on intrinsic optical signal (IOS) in rat hippocampus
alone or in combination with sodium salicylate to study its effects on auditory responses in the rat′s dorsal cortex of rat
to study its effects on hepatocellular carcinoma cells (HCC)

Biologische Aktivität

Selective, brain penetrant GABA B receptor antagonist (IC 50 = 34 μ M as measured in rat cortical membranes). Has higher affinity for postsynaptic versus presynaptic receptors.

Biochem/physiol Actions

CGP 35348 is a γ-aminobutyric acid-B (GABAB) receptor antagonist. It has a higher affinity towards post-versus presynaptic receptors that can penetrate the blood-brain barrier.

CGP 35348 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

3-aminopropyl(diethoxymethyl)-phosphinic acid ethyl ester ethyl 2-cyanoethyl(diethoxymethyl)phosphinate Kohlenstoff

Downstream Produkte

CGP 35348 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 38)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Ascent Scientific	4401179829988	customerservice@ascentscientific.co.uk	United Kingdom	279	60
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	3444	55
BOC Sciences	--	info@bocsci.com	USA	0	65
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44894	58

123690-79-9()Verwandte Suche:

Ethylmethylphosphinsure

CGP 35348
(3-AMINOPROPYL)(DIETHOXYMETHYL)PHOSPHINIC ACID
(3-Aminopropyl)(diethoxymethyl)phosphinic acid hydrate
CGP 35348 hydrate
P-(3-Aminopropyl)-P-(diethoxymethyl)phosphinic acid
Phosphinic acid, (3-aminopropyl)(diethoxymethyl)-
spatial learning,neuromuscular,neonatal damage,CGP-35348,brain penetrant,GABA Receptor,CGP35348,Gamma-aminobutyric acid Receptor,centrally,GABAB,CGP 35348,Inhibitor,γ-Aminobutyric acid Receptor,inhibit,active
Phosphinic acid, P-(3-aminopropyl)-P-(diethoxymethyl)-
123690-79-9
C8H20NO4P
GABA/Glycine receptor
GABA