Telomycin

Telomycin Struktur
19246-24-3
CAS-Nr.
19246-24-3
Bezeichnung:
Telomycin
Englisch Name:
Telomycin
Synonyma:
A-128;Nsc235069;Telomycin;Antibiotic 128;A 128-HYP, A 128-OP;18H-Dipyrrolo[2,1-C:2',1'-o][1,4,7,10,13,16,19,22,25]oxaoctaazacyclooctacosine;N-(L-βAsp-L-Ser-)Cyclo(L-Thr*-L-aThr-L-Ala-Gly-L-t3Hyp-3-(1H-indole-3-yl)Dha-β-methyl-L-Trp-4,4-dimethyl-L-aThr-L-c3Hyp-);L-Proline, L-β-aspartyl-L-seryl-L-threonyl-L-allothreonyl-L-alanylglycyl-(3S)-3-hydroxy-L-prolyl-α,β-didehydrotryptophyl-β-methyl-L-tryptophyl-(3S)-3-hydroxy-L-leucyl-3-hydroxy-, (11→3)-lactone, (3R)-;L-Proline, L-.beta.-aspartyl-L-seryl-L-threonyl-L-allothreonyl-L-alanylglycyl-trans-3-hydroxy-L-prolyl-erythro-3-hydroxy-L-leucyl-.beta.-methyl-L-tryptophyl-.alpha.,.beta.-didehydro-L-tryptophyl-cis-3-hydroxy-, .beta.1-lactone
CBNumber:
CB4882750
Summenformel:
C59H77N13O19
Molgewicht:
1272.33
MOL-Datei:
19246-24-3.mol

Telomycin Eigenschaften

alpha 
D28 -133° (c = 1 in 2:1 methanol-water)
Siedepunkt:
850.94°C (rough estimate)
Dichte
1.1263 (rough estimate)
Brechungsindex
1.6700 (estimate)
storage temp. 
Store at -20°C
Löslichkeit
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble; Water: slightly soluble
Aggregatzustand
A solid
pka
2.41±0.10(Predicted)

Sicherheit

Toxizität LD50 in mice (mg/kg): >1000 orally, i.v., i.p., i.m. (Tisch)

Telomycin Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Telomycin is a complex, high molecular weight depsipeptide discovered in 1958. The structure was subsequently solved in 1968. Telomycin possesses potent and highly selective activity against Gram positive bacteria in vitro and in vivo when given by intramuscular administration. Telomycin is poorly absorbed after oral administration. Despite its structural novelty, telomycin has received little attention.

Telomycin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Telomycin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 18)Lieferanten
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BOC Sciences
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TargetMol Chemicals Inc.
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Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
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Aladdin Scientific
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sales@aladdinsci.com United States 52927 58
Lynnchem 86-(0)29-85992781 17792393971
info@lynnchem.com China 4587 58
Novachemistry 44-20819178-90 02081917890
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Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6870 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684
sales@rrkchem.com China 55896 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11289 58
Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829
sales@mitachieve.com China 8864 58

  • Telomycin
  • N-(L-βAsp-L-Ser-)Cyclo(L-Thr*-L-aThr-L-Ala-Gly-L-t3Hyp-3-(1H-indole-3-yl)Dha-β-methyl-L-Trp-4,4-dimethyl-L-aThr-L-c3Hyp-)
  • 18H-Dipyrrolo[2,1-C:2',1'-o][1,4,7,10,13,16,19,22,25]oxaoctaazacyclooctacosine
  • A-128
  • Antibiotic 128
  • L-Proline, L-.beta.-aspartyl-L-seryl-L-threonyl-L-allothreonyl-L-alanylglycyl-trans-3-hydroxy-L-prolyl-erythro-3-hydroxy-L-leucyl-.beta.-methyl-L-tryptophyl-.alpha.,.beta.-didehydro-L-tryptophyl-cis-3-hydroxy-, .beta.1-lactone
  • Nsc235069
  • A 128-HYP, A 128-OP
  • L-Proline, L-β-aspartyl-L-seryl-L-threonyl-L-allothreonyl-L-alanylglycyl-(3S)-3-hydroxy-L-prolyl-α,β-didehydrotryptophyl-β-methyl-L-tryptophyl-(3S)-3-hydroxy-L-leucyl-3-hydroxy-, (11→3)-lactone, (3R)-
  • 19246-24-3
  • C59H77N13O19
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