DOBUTAMINE Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R63:Kann das Kind im Mutterleib möglicherweise schädigen.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Verwenden
Dobutamine is predominantly a β1-agonist, with some activity at β2-
receptors. Its primary effect is an increase in cardiac output as a consequence
of increased contractility and HR and decreased afterload. Systolic arterial
pressure may therefore increase, but peripheral resistance is reduced or
unchanged. It is primarily used as an inotrope (inodilator) in low CO states.
D obutamine increases SA node automaticity and conduction velocity in the
atria, ventricles and AV node, with tachyarrhythmias occurring at higher
doses. Dobutamine is administered as an i.v. infusion at a dose range of 0.5–
40 μg kg–1 min–1.
Definition
ChEBI: A catecholamine that is 4-(3-aminobutyl)phenol in which one of the hydrogens attached to the nitrogen is substituted by a 2-(3,4-dihydroxyphenyl)ethyl group. A beta1-adrenergic receptor agonist that has cardiac stimulan
action without evoking vasoconstriction or tachycardia, it is used as the hydrochloride to increase the contractility of the heart in the management of acute heart failure.
DOBUTAMINE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
