Pyrazofurin

Pyrazofurin Struktur
30868-30-5
CAS-Nr.
30868-30-5
Englisch Name:
Pyrazofurin
Synonyma:
PRZF;47599;A-23813;nsc143095;pyrazofurin;pirazofurin;Pyrazomycin;Pyrozofurin;compound47599;β-Pyrazofurin
CBNumber:
CB5276253
Summenformel:
C9H13N3O6
Molgewicht:
259.22
MOL-Datei:
30868-30-5.mol

Pyrazofurin Eigenschaften

Siedepunkt:
584.4±50.0 °C(Predicted)
Dichte
1.785±0.06 g/cm3(Predicted)
storage temp. 
-20°C
Löslichkeit
DMSO, Water (Slightly)
pka
7.17±0.50(Predicted)
Aggregatzustand
powder
Farbe
white to light brown
Optische Aktivität
[α]/D -49 to -39°, c = 0.5 in H2O
Stabilität:
Hygroscopic

Sicherheit

Pyrazofurin Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Geldanamycin (G304500) derivative.

Definition

ChEBI: A C-glycosyl compound that is 4-hydroxy-1H-pyrazole-5-carboxamide in which the hydrogen at position 3 has been replaced by a beta-D-ribofuranosyl group.

Enzyminhibitor

This pyrimidine nucleoside (FW = 261.23 g/mol), also known as pyrazomycin, exhibits antineoplastic activity and inhibits cell proliferation and DNA synthesis in cells by inhibiting orotidylate decarboxylase (uridine 5'-phosphate synthase). Pyrazofurin, also known as 3,b-D-ribofuranosyl-4- hydroxypyrazole-5-carboxamide, is the prodrug of the 5’-phosphate derivative. Target(s): adenosylhomocysteinase; 5-aminoimidazole-4- carboxamide-1-b-D-ribofuranosyl 5'-monophosphate formyltransferase; orotate phosphoribosyltransferase; orotidylate decarboxylase, or UMP synthase.

Pyrazofurin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Pyrazofurin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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30868-30-5()Verwandte Suche:


  • 3-beta-d-ribofuranosyl-4-hydroxypyrazole-5-carboxamide
  • 4-hydroxy-3-beta-d-ribofuranosyl-1h-pyrazole-5-carboxamid
  • 4-hydroxy-3-beta-d-ribofuranosyl-1h-pyrazole-5-carboxamide
  • antibiotica23813
  • beta-pyrazomycin
  • compound47599
  • nsc143095
  • pirazofurin
  • pyrazofurin
  • PYRAZOFURIN MONOHYDRATE
  • 4-HYDROXY-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLE-5-CARBOXAMIDE MONOHYDRATE
  • 47599
  • A-23813
  • 1H-Pyrazole-5-carboxamide, 4-hydroxy-3-beta-D-ribofuranosyl-
  • 4-Hydroxy-3-beta-D-ribofuranosylpyrazole-5-carboxamide
  • PRZF
  • Pyrazole-3-carboxamide, 4-hydroxy-5-beta-L-ribofuranosyl-
  • Pyrazomycin
  • Pyrozofurin
  • 1H-Pyrazole-5-carboxamide, 4-hydroxy-3-β-D-ribofuranosyl-
  • β-Pyrazofurin
  • --Pyrazofurin
  • Pyrazomycin Ⅰ
  • 30868-30-5
  • Bases & Related Reagents
  • Intermediates & Fine Chemicals
  • Nucleotides
  • Pharmaceuticals
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