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3-Iodo-L-tyrosin Produkt Beschreibung

3-IODO-L-TYROSINE Struktur
70-78-0
CAS-Nr.
70-78-0
Bezeichnung:
3-Iodo-L-tyrosin
Englisch Name:
3-IODO-L-TYROSINE
Synonyma:
H-3-I-TYR-OH;3-I-L-Tyr-OH;Iodotyrosine;H-TYR(3-I)-OH;H-TYR(M-I)-OH;3-Iodo-Tyr-OH;H-3-IODO-TYR-OH;H-L-TYR(3-I)-OH;3-IODO-TYROSINE;3-IODO-L-TYROSINE
CBNumber:
CB5721061
Summenformel:
C9H10INO3
Molgewicht:
307.09
MOL-Datei:
70-78-0.mol

3-Iodo-L-tyrosin Eigenschaften

Schmelzpunkt:
210 °C (dec.)(lit.)
Dichte
1.7280 (estimate)
storage temp. 
2-8°C
Löslichkeit
dilute aqueous acid: soluble
pka
2.21±0.20(Predicted)
Siedepunkt:
391.0±42.0 °C(Predicted)
Aggregatzustand
Solid
Farbe
White to off-white
Sensitive 
Light Sensitive
Merck 
14,5047
BRN 
2941266
InChIKey
UQTZMGFTRHFAAM-ZETCQYMHSA-N
CAS Datenbank
70-78-0(CAS DataBase Reference)
EPA chemische Informationen
L-Tyrosine, 3-iodo- (70-78-0)

Sicherheit

S-Sätze: 24/25
WGK Germany  3
8-10-23
HS Code  29225090

3-Iodo-L-tyrosin Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:

S24/25:Berührung mit den Augen und der Haut vermeiden.

Chemische Eigenschaften

White Solid

Verwenden

A novel flavoprotein responsible for iodide salvage in thyroid glands. A tyrosine hydroxylase inhibitor.

Definition

ChEBI: The monoiodotyrosine that is L-tyrosine carrying an iodo-substituent at position C-3 of the benzyl group.

läuterung methode

Likely impurities are tyrosine, diiodotyrosine and iodide. Crystallise it by dissolving it in concentrated ammonia (~200mg in ~20mL), evaporate to ~5mL and NH4Cl is added to pH4.5—5.0. After a few hours at 0o, the amino acid crystallises in needles. It is filtered off, washed with a little ice-cold H2O and dried in a vacuum. Alternatively dissolve it in dilute ammonia at room temperature, then add dilute acetic acid to pH 6. Store it at 0o. Recrystallisation of ~250mg from H2O (~5mL) removes any diiodotyrosine. It is an inhibitor of tyrosine hydroxylase with a Ki of ~500nM. [Harrington & Rivers Biochem J 38 320 1944, Rivers Chem & Ind (London) 21 1956, Beilstein 14 III 1562, 14 IV 1562.]

3-Iodo-L-tyrosin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


3-Iodo-L-tyrosin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 150)Lieferanten
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Henan DaKen Chemical CO.,LTD.
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Suzhou Ryan Pharmaceutical Technology Co., Ltd. +86-512-68780025
+86-512-68780026 sales@ryanchem.com China 153 62
Shifang ShengYuan Technology Co., Ltd. 13402890778,
qq:1120021438 1120021438@qq.com China 164 56

70-78-0(3-Iodo-L-tyrosin)Verwandte Suche:


  • 3-iodine-L- tyrosine
  • 3-I-L-Tyr-OH
  • 3-Iodo-L-tyrosine≥ 98% (HPLC)
  • H-L-Phe(3-I,4-OH)-OH
  • L-TYROSINE, 3-IODO-
  • H-TYR(M-I)-OH
  • H-TYR(3-I)-OH
  • H-L-TYR(3-I)-OH
  • H-3-IODO-TYR-OH
  • H-3-I-PHE(4-OH)-OH
  • H-3-I-TYR-OH
  • 3-IODO-TYROSINE
  • 3-IODO-L-TYROSINE
  • 3-MONOIODO-L-TYROSINE
  • S(-)-3-IODO-4-HYDROXY-PHENYLAMINE
  • M-IODO-L-TYROSINE
  • 3-Monoiodo-L-tyrosine 3-Iodo-L-tyrosine
  • Iodotyrosine
  • (2S)-2-amino-3-(4-hydroxy-3-iodophenyl)propanoic acid
  • 3-IODO-L -TYROSINE 97%
  • 3-Iodo-L-tyrosine,97%
  • 3-Iodo-Tyr-OH
  • 3-Iodo-L-tyrosine,3-Monoiodo-L-tyrosine
  • 3-Iodo-L-tyrosine, 97% 1GR
  • 3-Iodo-4-hydroxyphenylalanine
  • 4-Hydroxy-3-iodophenylalanine
  • (S)-2-AMino-3-(4-hydroxy-3-iodophenyl)propanoic acid
  • (2S)-2-ammonio-3-(4-hydroxy-3-iodophenyl)propanoate
  • 70-78-0
  • C9H10INO3
  • IC6H34OHCH2CHNH2CO2H
  • Tyrosine Derivatives
  • Unnatural Amino Acid Derivatives
  • Peptide Synthesis
  • Specialty Synthesis
  • amino
  • Unusual Amino Acids
  • Amino Acids 13C, 2H, 15N
  • Amino Acids
  • Biochemistry
  • Biological-modified Amino Acids
  • Amino Acids & Derivatives
  • Inhibitors
  • Aromatics
  • Chiral Reagents
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