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3-IODO-L-TYROSINE

3-IODO-L-TYROSINE
3-IODO-L-TYROSINE
CAS No.
70-78-0
Chemical Name:
3-IODO-L-TYROSINE
Synonyms
3-I-L-Tyr-OH;H-3-I-TYR-OH;Iodotyrosine;H-TYR(3-I)-OH;H-TYR(M-I)-OH;3-Iodo-Tyr-OH;H-3-IODO-TYR-OH;H-L-TYR(3-I)-OH;3-IODO-TYROSINE;3-IODO-L-TYROSINE
CBNumber:
CB5721061
Molecular Formula:
C9H10INO3
Formula Weight:
307.09
MOL File:
70-78-0.mol

3-IODO-L-TYROSINE Properties

Melting point:
210 °C (dec.)(lit.)
Density 
1.7280 (estimate)
storage temp. 
2-8°C
solubility 
dilute aqueous acid: soluble
form 
Solid
color 
White to off-white
Sensitive 
Light Sensitive
Merck 
14,5047
CAS DataBase Reference
70-78-0(CAS DataBase Reference)

SAFETY

Safety Statements  24/25
WGK Germany  3
8-10-23

3-IODO-L-TYROSINE price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich I8250 3-Iodo-L-tyrosine 70-78-0 1g $51.2 2018-11-13 Buy
Sigma-Aldrich I8250 3-Iodo-L-tyrosine 70-78-0 5g $186 2018-11-13 Buy
TCI Chemical I0075 3-Iodo-L-tyrosine >98.0%(T) 70-78-0 1g $38 2017-11-08 Buy
TCI Chemical I0075 3-Iodo-L-tyrosine >98.0%(T) 70-78-0 5g $134 2017-11-08 Buy
Alfa Aesar H63789 3-Iodo-L-tyrosine, 98% 70-78-0 1g $28.3 2018-11-13 Buy

3-IODO-L-TYROSINE Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

A novel flavoprotein responsible for iodide salvage in thyroid glands. A tyrosine hydroxylase inhibitor.

Definition

ChEBI: The monoiodotyrosine that is L-tyrosine carrying an iodo-substituent at position C-3 of the benzyl group.

Purification Methods

Likely impurities are tyrosine, diiodotyrosine and iodide. Crystallise it by dissolving it in concentrated ammonia (~200mg in ~20mL), evaporate to ~5mL and NH4Cl is added to pH4.5—5.0. After a few hours at 0o, the amino acid crystallises in needles. It is filtered off, washed with a little ice-cold H2O and dried in a vacuum. Alternatively dissolve it in dilute ammonia at room temperature, then add dilute acetic acid to pH 6. Store it at 0o. Recrystallisation of ~250mg from H2O (~5mL) removes any diiodotyrosine. It is an inhibitor of tyrosine hydroxylase with a Ki of ~500nM. [Harrington & Rivers Biochem J 38 320 1944, Rivers Chem & Ind (London) 21 1956, Beilstein 14 III 1562, 14 IV 1562.]

3-IODO-L-TYROSINE Preparation Products And Raw materials

Raw materials

Preparation Products


3-IODO-L-TYROSINE Suppliers

Global( 128)Suppliers
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Henan DaKen Chemical CO.,LTD.
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Alfa Aesar 400-610-6006; 021-67582000
021-67582001/03/05 saleschina@alfa-asia.com China 30308 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 / 800-988-0390
021-67121385 Sales-CN@TCIchemicals.com China 24654 81

70-78-0(3-IODO-L-TYROSINE)Related Search:


  • 3-Iodo-4-hydroxyphenylalanine
  • 4-Hydroxy-3-iodophenylalanine
  • amino
  • 3-iodine-L- tyrosine
  • 3-I-L-Tyr-OH
  • 3-Iodo-L-tyrosine≥ 98% (HPLC)
  • H-L-Phe(3-I,4-OH)-OH
  • L-TYROSINE, 3-IODO-
  • H-TYR(M-I)-OH
  • H-TYR(3-I)-OH
  • H-L-TYR(3-I)-OH
  • H-3-IODO-TYR-OH
  • H-3-I-PHE(4-OH)-OH
  • H-3-I-TYR-OH
  • 70-78-0
  • 3-IODO-TYROSINE
  • 3-IODO-L-TYROSINE
  • 3-MONOIODO-L-TYROSINE
  • S(-)-3-IODO-4-HYDROXY-PHENYLAMINE
  • M-IODO-L-TYROSINE
  • Tyrosine Derivatives
  • Unnatural Amino Acid Derivatives
  • Peptide Synthesis
  • Specialty Synthesis
  • 3-Monoiodo-L-tyrosine 3-Iodo-L-tyrosine
  • Iodotyrosine
  • C9H10INO3
  • (2S)-2-amino-3-(4-hydroxy-3-iodophenyl)propanoic acid
  • 3-IODO-L -TYROSINE 97%
  • Unusual Amino Acids
  • Amino Acids 13C, 2H, 15N
  • Amino Acids
  • Biochemistry
  • Biological-modified Amino Acids
  • Amino Acids & Derivatives
  • Inhibitors
  • IC6H34OHCH2CHNH2CO2H
  • 3-Iodo-L-tyrosine,97%
  • 3-Iodo-Tyr-OH
  • 3-Iodo-L-tyrosine,3-Monoiodo-L-tyrosine
  • Aromatics
  • Chiral Reagents
  • 3-Iodo-L-tyrosine, 97% 1GR
  • (S)-2-AMino-3-(4-hydroxy-3-iodophenyl)propanoic acid
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