CAY10499

CAY10499 Struktur
359714-55-9
CAS-Nr.
359714-55-9
Englisch Name:
CAY10499
Synonyma:
CAY10499;CAY10499 Exclusive;QTENHWTVRQKWRI-UHFFFAOYSA-N;Inhibitor,inhibit,MAGLIN5,MAGL IN 5,FAAH,Fatty acid amide hydrolase,Monoacylglycerol lipase,MAGL;Carbamic acid, N-[4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-2-methylphenyl]-, phenylmethyl ester
CBNumber:
CB62590413
Summenformel:
C18H17N3O5
Molgewicht:
355.34
MOL-Datei:
359714-55-9.mol

CAY10499 Eigenschaften

Dichte
1.31±0.1 g/cm3(Predicted)
Löslichkeit
Soluble in DMSO
Aggregatzustand
crystalline solid
pka
13.31±0.70(Predicted)

Sicherheit

CAY10499 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

CAY10499 is a non-selective lipase inhibitor (IC50s = 144, 90, and 14 nM for human recombinant MAGL, HSL, and FAAH, respectively). It also inhibits ATGL, DAGLa, ABHD6, and CES1 by 95, 60, 90, and 95%, respectively, when used at a concentration of 5 mM. CAY10499 inhibits the growth of MCF-7, MDA-MB-231, COV318, and OVCAR-3 cancer cells (IC50s = 4.2, 46, 106.7, and 79.8 μM, respectively). In vivo, CAY10499 reduces FRUC diet- and AIN-93M diet-induced increases in cytosolic lipase activity in rats.

CAY10499 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


CAY10499 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 32)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581
sales@chemhifuture.com China 3136 58
TargetMol Chemicals Inc.
+1-781-999-5354
support@targetmol.com United States 19973 58
Aladdin Scientific
+1-833-552-7181
sales@aladdinsci.com United States 52927 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11289 58
Shanghai Beckham Medical Technology Co., Ltd 021-13816613772 13816613772
huahero21@sina.com China 359 55
BOC Sciences 16314854226
info@bocsci.com United States 9926 65
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369
3477467573@qq.com China 8618 58
Nantong Hi-Future Biotechnology Co., Ltd 18051384581
sales@chemhifuture.com China 3061 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195
sales@tybiochem.com China 5143 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
customer_service@efebio.com China 8740 58

  • CAY10499
  • QTENHWTVRQKWRI-UHFFFAOYSA-N
  • CAY10499 Exclusive
  • Inhibitor,inhibit,MAGLIN5,MAGL IN 5,FAAH,Fatty acid amide hydrolase,Monoacylglycerol lipase,MAGL
  • Carbamic acid, N-[4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-2-methylphenyl]-, phenylmethyl ester
  • 359714-55-9
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