Lanosterin
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- CAS-Nr.
- 79-63-0
- Bezeichnung:
- Lanosterin
- Englisch Name:
- LANOSTEROL
- Synonyma:
- Lanosterin;Lanster;DUSOGEL;lanostcrol;LANOSTEROL;botalanbase;CRYPTOSTEROL;Criptosterol;Kriptosterol;Kryp-tosterol
- CBNumber:
- CB6266873
- Summenformel:
- C30H50O
- Molgewicht:
- 426.73
- MOL-Datei:
- 79-63-0.mol
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Lanosterin Eigenschaften
- Schmelzpunkt:
- 137 °C
- alpha
- D20 +62.0° (chloroform)
- Siedepunkt:
- 482.1°C (rough estimate)
- Dichte
- 0.9600 (rough estimate)
- Brechungsindex
- 1.4910 (estimate)
- storage temp.
- -20°C
- Löslichkeit
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- pka
- 15.16±0.70(Predicted)
- Aggregatzustand
- powder
- Farbe
- white
- Geruch (Odor)
- at 100.00?%. bland
- Merck
- 5360
- InChIKey
- CAHGCLMLTWQZNJ-BQNIITSRSA-N
- LogP
- 10.521 (est)
- CAS Datenbank
- 79-63-0(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| WGK Germany |
1 |
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| RTECS-Nr. |
OE3360000 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P302+P352 |
BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P304+P340 |
BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
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Lanosterin Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Lanosterol is a naturally-occurring sterol and biosynthetic precursor of several animal, fungal, and protozoan steroids, including cholesterol and ergosterol. Defects in the processing of lanosterol contribute to a wide variety of disorders, including the formation of cataracts. Similarly, certain fungicides act by blocking lanosterol processing by fungi.
Verwenden
Lanosterol has been used:
- as a standard in HPLC for the quantification in testis samples
- in S-adenosyl-L-methionine:Δ24-sterol-C-methyltransferase (SMT) assay
- to treat wild-type cells growing in rich medium to know its effects on Sre1 protein
Definition
ChEBI: A tetracyclic triterpenoid that is lanosta-8,24-diene substituted by a beta-hydroxy group at the 3beta position. It is the compound from which all steroids are derived.
Allgemeine Beschreibung
Lanosterol, an amphipathic molecule, that is produced by?lanosterol?synthase (LSS). It is enriched in the lens.
läuterung methode
If very impure, then it should be acetylated, converted to the dibromide acetate [crystallised from EtOAc with slow cooling, m 168-170o, [] D +214o (CHCl3)], de-brominated with Zn dust to give the acetate (below) which is recrystallised from 3-4 parts of Me2CO/MeOH (4:1) and hydrolysed as for stigmasterol (below). Recrystallise it from anhydrous MeOH. Dry it in vacuo over P2O5 for 3hours at 90o. The purity is checked by proton magnetic resonance. The acetate crystallises from MeOH with m 131-133o and [ ] 25D +62o (c 1,CHCl3). [Block & Urech Biochemical Preparations 6 32 1958. van Tamelen et al. J Am Chem Soc 104 6479, 6480 1982, Beilstein 6 III 2880, 6 IV 4188.]
Lanosterin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Lanosterin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 272)Lieferanten
79-63-0(Lanosterin)Verwandte Suche:
- (3-beta)-lanosta-24-dien-3-ol
- (3-beta)-lanosta-8,24-dien-3-ol
- lanosta-8,24-dien-3-beta-ol
- Lanosta-8,24-dien-3beta-ol
- Lanosta-8,24-dien-3-ol
- Lanosta-8,24-dien-3-ol, (3beta)-
- Lanosta-8,24-dienol
- lanostadien-3-beta-ol
- lanosterol50-60%
- Lanster
- 24-dien-3-ol,(3.beta.)-Lanosta-8
- CRYPTOSTEROL
- ISOCHOLESTEROL
- 3BETA-HYDROXY-8,24-LANOSTADIENE
- 8,24-LANOSTADIEN-3BETA-OL
- 8,24-LANOSTADIEN-3-OL
- 8,24-LANOSTADIENE-3BETA-OL
- 8,24,(5-ALPHA)-CHOLESTADIEN-4,4,14-ALPHA-TRIMETHYL-3-BETA-OL
- 8,24,(5ALPHA)-CHOLESTADIEN-4,4,14ALPHA-TRIMETYHL-3BETA OL
- (3S,5S,10S,13S,14S)-4,4,10,13,14-pentamethyl-17-[(2S)-6-methylhept-5-en-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
- Lanosta-8,24-dien-3-ol,(3b)-
- Botalan base 138
- botalanbase
- Cholesta-8,24-dien-3-ol, 4,4,14-trimethyl-, (3beta,5alpha)-
- lanosterol approx. 97%
- LANOSTEROL ABOUT 55-65%
- LANOSTEROL 95%
- 3β-hydroxy-8,24-lanostadiene
- 4,4,10,13,14-pentamethyl-17-(6-methylhept-5-en-2-yl)-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
- LANOSTEROL(RG)
- DUSOGEL
- LANOSTEROL ~60% PURE
- 3β-Hydroxy-8,24-lanostadiene, 8,24-Lanostadien-3β-ol
- 5α-Lanosta-8,24-dien-3β-ol
- 5α-Lanosta-8,24-diene-3β-ol
- Criptosterol
- Kriptosterol
- 8,24(5α)-Cholestadien-4,4,14α-triMethyl-3β-ol
- Kryp-tosterol
- LANOSTEROL (FROM NATURAL SOURCES)
- LANOSTA-8,24-DIEN-3-OL;LANOSTEROL
- lanostcrol
- LANOSTEROL, >/=93%, POWDER
- LANOSTEROL
- (3S,5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-[(2R)-6-methylhept-5-en-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
- (3β)-Lanosta-8,24-dien-3-ol
- Lanosterol pure, ~60%
- Lanosterol (Isocholesterol)
- Lanosterol (Isocholesterol) - Lanosterol 60%
- Lanosterol >
- Lanosterol (Technical Grade)
- Lanosta-8,24-dien-3-ol, (3β)-
- LANOSTEROL USP/EP/BP
- Lanosterin
- 8,24-Lanostadien-3β-ol
- (3S,5R,10S,13R,14R,17R)-4,4,10,13,14-Pentamethyl-17-((R)-6-methylhept-5-en-2-yl)-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
- Garlic oil 8008-99-9
- 8, 24, (5α)-CHOLESTADIEN-4, 4, 14α-TRIMETHYL-3β-OL
