PSI-7977-13C-d3

PSI-7977-13C-d3 Struktur
2070009-25-3
CAS-Nr.
2070009-25-3
Englisch Name:
PSI-7977-13C-d3
Synonyma:
[13C,2H3]-Sofosbuvir;isopropyl((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-(methyl-13C-d3)tetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate;Sofosbuvir 13CD3Q: What is Sofosbuvir 13CD3 Q: What is the CAS Number of Sofosbuvir 13CD3 Q: What is the storage condition of Sofosbuvir 13CD3 Q: What are the applications of Sofosbuvir 13CD3
CBNumber:
CB64666758
Summenformel:
C2113CH26D3FN3O9P
Molgewicht:
0
MOL-Datei:
Mol file

PSI-7977-13C-d3 Eigenschaften

storage temp. 
Store at -20°C
Löslichkeit
DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 0.2 mg/ml
Aggregatzustand
A solid

Sicherheit

PSI-7977-13C-d3 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

PSI-7977-13C-d3 is intended for use as an internal standard for the quantification of PSI-7977 by GC- or LC-MS. PSI-7977 is a phosphoramidate prodrug of PSI-7851, a nucleoside analog that, when phosphorylated, inhibits the RNA-dependent RNA polymerase of hepatitis C virus (EC50 = 92 nM). PSI-7977 is effective in vitro and in vivo.

Verwenden

PSI-7977-13CD3 is the isotope labelled analog of PSI-7977. PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

PSI-7977-13C-d3 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


PSI-7977-13C-d3 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 15)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ANHUI WITOP BIOTECH CO., LTD
+8615255079626
eric@witopchemical.com China 23556 58
Shanghai Payne Pharmaceutical Technology Co.Ltd
021-58123769 18678586262
info@paynepharm.com China 1354 58
Artis Biotech Co. Ltd. 19138486554 18582380095
sales@artisbio.com China 2964 58
Shanghai Payne Pharmaceutical Technology Co.Ltd 021-58123769 17721400256
info@paynepharm.com China 1285 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11289 58
PureChemland Co.,Ltd. 19150123681
3848291069@qq.com China 3249 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
customer_service@efebio.com China 8740 58
Hubei Moco Chemical Co., Ltd. 18627756402
3001051413@qq.com China 10019 58
United States Biological --
sales@advtechind.com United States 6106 58

  • [13C,2H3]-Sofosbuvir
  • isopropyl((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-(methyl-13C-d3)tetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
  • Sofosbuvir 13CD3Q: What is Sofosbuvir 13CD3 Q: What is the CAS Number of Sofosbuvir 13CD3 Q: What is the storage condition of Sofosbuvir 13CD3 Q: What are the applications of Sofosbuvir 13CD3
  • 2070009-25-3
  • C2113CH26D3FN3O9P
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