PSI-7977-13C-d3

PSI-7977-13C-d3 구조식 이미지
카스 번호:
2070009-25-3
상품명:
PSI-7977-13C-d3
동의어(영문):
[13C,2H3]-Sofosbuvir;isopropyl((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-(methyl-13C-d3)tetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate;Sofosbuvir 13CD3Q: What is Sofosbuvir 13CD3 Q: What is the CAS Number of Sofosbuvir 13CD3 Q: What is the storage condition of Sofosbuvir 13CD3 Q: What are the applications of Sofosbuvir 13CD3
CBNumber:
CB64666758
분자식:
C2113CH26D3FN3O9P
포뮬러 무게:
0
MOL 파일:
Mol file

PSI-7977-13C-d3 속성

저장 조건
Store at -20°C
용해도
DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 0.2 mg/ml
물리적 상태
고체

안전

PSI-7977-13C-d3 C화학적 특성, 용도, 생산

개요

PSI-7977-13C-d3 is intended for use as an internal standard for the quantification of PSI-7977 by GC- or LC-MS. PSI-7977 is a phosphoramidate prodrug of PSI-7851, a nucleoside analog that, when phosphorylated, inhibits the RNA-dependent RNA polymerase of hepatitis C virus (EC50 = 92 nM). PSI-7977 is effective in vitro and in vivo.

용도

PSI-7977-13CD3 is the isotope labelled analog of PSI-7977. PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

PSI-7977-13C-d3 준비 용품 및 원자재

원자재

준비 용품


PSI-7977-13C-d3 공급 업체

글로벌( 16)공급 업체
공급자 전화 이메일 국가 제품 수 이점
ANHUI WITOP BIOTECH CO., LTD
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eric@witopchemical.com China 23556 58
Shanghai Payne Pharmaceutical Technology Co.Ltd
021-58123769 18678586262
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Artis Biotech Co. Ltd. 19138486554 18582380095
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Hubei Moco Chemical Co., Ltd. 18627756402
3001051413@qq.com China 10009 58
Shanghai Payne Pharmaceutical Technology Co.Ltd 021-58123769 17721400256
info@paynepharm.com China 1285 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
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PureChemland Co.,Ltd. 19150123681
3848291069@qq.com China 3249 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
customer_service@efebio.com China 8740 58
Nanjing Shizhou Biology Technology Co.,Ltd 17301488900
judy.xia@synzest.com China 13698 58
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