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Dolutegravir 2-Desfluoro Impurity

1863916-88-4

CAS-Nr.: 1863916-88-4

Englisch Name:: Dolutegravir 2-Desfluoro Impurity

Synonyma:: 4-Fluoro Dolutegravir;Dolutegravir Impurity G;Dolutegravir Impurity 50;Dolutegravir Impurity 47;Defluoro Dolutegravir (>85%);Dolutegravir 4-Fluoro Impurity;Dolutegravir 2-Desfluoro Impurity;(4R,12aS)-N-(4-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-/Dolutegravir impurity

CBNumber:: CB64796145

Summenformel:: C20H20FN3O5

Molgewicht:: 401.39

MOL-Datei:: 1863916-88-4.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 34

Dolutegravir 2-Desfluoro Impurity Eigenschaften

Siedepunkt:: 675.7±55.0 °C(Predicted)

Dichte: 1.49±0.1 g/cm3(Predicted)

Löslichkeit: DMSO (Slightly), Methanol (Slightly, Heated)

Aggregatzustand: Solid

pka: 4.50±1.00(Predicted)

Farbe: Off-White to Light Brown

Sicherheit

Dolutegravir 2-Desfluoro Impurity Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Defluoro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir 2-Desfluoro Impurity Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Dolutegravir 2-Desfluoro Impurity Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 34)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
CR Corporation Limited	+8613062833949	fred.wen@crcorporation.cn	China	8645	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12373	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11922	58
ShenZhen H&D Pharmaceutical Technology Co., LTD	+8618627948422	sale@hdimpurity.com	China	3681	58
Moxin Chemicals	+86-17320513646 +8617320513646	anna@molcoo.com	China	10000	58
S.Z. PhyStandard Bio-Tech. Co., Ltd.	0755-4000505016 13380397412	3001272453@qq.com	China	5158	50
ChemStrong Scientific Co.,Ltd	0755-0755-66853366 13670046396	sales@chem-strong.com	China	18333	56
Shanghai CR Corporation Limited	13062833949; 4006653949 4006653949	fred.wen@crcorporation.cn	China	9753	58
Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.	020-89854820	sales@jzpharma.cn	China	1487	58
Nanjing zehe Pharmaceutical Technology Co., Ltd	17768115366	henry124604479@163.com	China	230	58

2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-/Dolutegravir impurity
Dolutegravir impurity 4/Defluoro Dolutegravir/(4R,12aS)-N-(4-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Dolutegravir Impurity G
Dolutegravir 2-Desfluoro Impurity
2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
(4R,12aS)-N-(4-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Dolutegravir Impurity 47
Dolutegravir Impurity 50
4-Fluoro Dolutegravir
Dolutegravir 4-Fluoro Impurity
Defluoro Dolutegravir (>85%)
1863916-88-4