(3β,18α,20β)-3-Hydroxy-11-oxoolean-12-en-29-sure
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- CAS-Nr.
- 1449-05-4
- Bezeichnung:
- (3β,18α,20β)-3-Hydroxy-11-oxoolean-12-en-29-sure
- Englisch Name:
- 18alpha-Glycyrrhetinic acid
- Synonyma:
- Nsc 35350;Triterpene;Ccris 3963;Brn 2956366;Einecs 215-907-9;18α-Glycyrrhetinic;18a-Glycyrrhetic acid;18α-Glycyrrhetic acid;18A-GLYCYRRHETINIC ACID;beta-glycyrrhetinicacid
- CBNumber:
- CB7172205
- Summenformel:
- C30H46O4
- Molgewicht:
- 470.68
- MOL-Datei:
- 1449-05-4.mol
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(3β,18α,20β)-3-Hydroxy-11-oxoolean-12-en-29-sure Eigenschaften
- Schmelzpunkt:
- 331-333°C
- Siedepunkt:
- 492.11°C (rough estimate)
- Dichte
- 0.9967 (rough estimate)
- Brechungsindex
- 1.4800 (estimate)
- storage temp.
- 2-8°C
- Löslichkeit
- DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- 4.71±0.70(Predicted)
- Farbe
- White to Off-White
- LogP
- 6.570 (est)
- CAS Datenbank
- 1449-05-4(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn |
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| R-Sätze: |
22 |
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| S-Sätze: |
ection |
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| WGK Germany |
3 |
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| RTECS-Nr. |
RK0190000 |
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| HS Code |
29189900 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
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(3β,18α,20β)-3-Hydroxy-11-oxoolean-12-en-29-sure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
Verwenden
18α-Glycyrrhetinic acid may be used to synthesize:
- 3-keto-18α-glycyrrhetinic acid
- methyl esters of 18α-glycyrrhetinic acid
- methyl esters of 3-keto-18α-glycyrrhetinic acid
Allgemeine Beschreibung
18α-Glycyrrhetinic acid (18α-GA) is a bioactive triterpenoid found in licorice. It shows selective inhibition of 11-HSD1 (11-hydroxysteroid dehydrogenase 1). It also shows anti-proliferative and apoptotic effect on hepatic stellate cells (HSCs).
(3β,18α,20β)-3-Hydroxy-11-oxoolean-12-en-29-sure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(3β,18α,20β)-3-Hydroxy-11-oxoolean-12-en-29-sure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 181)Lieferanten
1449-05-4((3β,18α,20β)-3-Hydroxy-11-oxoolean-12-en-29-sure)Verwandte Suche:
- 3-beta-hydroxy-11-oxo-18-alpha-olean-12-en-30-oicaci
- 3-beta-hydroxy-11-oxo-18-alpha-olean-12-en-30-oicacid
- beta-glycyrrhetinicacid
- GLYCYRRHETINIC ACID, 18A-
- 3BETA-HYDROXY-11-OXO-18ALPHA,20BETA-OLEAN-12-EN-29-OIC ACID
- 18A-GLYCYRRHETINIC ACID
- 18ALPHA-GLYCYRRHETINIC ACID
- Triterpene
- Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3.beta.,18.alpha.,20.beta.)-
- (18α)-3β-Hydroxy-11-oxoolean-12-en-30-oic acid
- 3β-hydroxy-11-oxo-18α,20β-olean-12-en-29-oic acid
- 18-ISOGLYCYRRHETINICACID
- 18-ALPHA-GLYCYRRHETICACID
- (3beta,18alpha,20beta)-3-Hydroxy-11-oxoolean-12-en-29-oic acid
- 18α-Glycyrrhetinic
- 18-alpha-Olean-12-en-30-oic acid, 3-beta-hydroxy-11-oxo-
- Brn 2956366
- Ccris 3963
- Einecs 215-907-9
- Nsc 35350
- 18a-Glycyrrhetic acid
- 18alpha-Glycyrrhetinic acid >=95%
- Glycyrrhetinic acid (α-type)
- 18α-Glycyrrhetinic acid, 95%, from Glycyrrhiza uralensis Fisch.
- Glycyrrhetinic acid 1449-05-4
- 18a-Glycyrrhetic acid,95%
- 18α-Glycyrrhetinic Acid,HPLC≥98%
- Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3β,18α,20β)-
- Enoxolone EP Impurity A
- 18α-Glycyrrhetinic Acid
- Enoxolone Impurity 1 (Enoxolone EP Impurity A)
- (2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bS)-10-hy droxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3 ,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-ic osahydropicene-2-carboxylic acid
- 18α-Glycyrrhetic acid
- 18 α-glycyrrhetintic acid
- Magnesium Isoglycyrrhetinic Acid Impurity C
- 1449-05-4
- Chiral Building Blocks
- Asymmetric Synthesis
- Complex Molecules
- Inhibitors
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- sy
- The group of Liquorice
- Tri-Terpenoids
