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Enoxolon Produkt Beschreibung

Enoxolone Struktur
471-53-4
CAS-Nr.
471-53-4
Bezeichnung:
Enoxolon
Englisch Name:
Enoxolone
Synonyma:
PO 12;GM 1658;STX 352;18 BETA;biosone;ENOXOLONE;ENOLOXONE;NSC 35347;Arthrodont;glycyrrhetin
CBNumber:
CB8474793
Summenformel:
C30H46O4
Molgewicht:
470.68
MOL-Datei:
471-53-4.mol

Enoxolon Eigenschaften

Schmelzpunkt:
292-295 °C(lit.)
alpha 
165 º (c=1, CHCl3,on dry ba)
Siedepunkt:
492.11°C (rough estimate)
Dichte
0.9967 (rough estimate)
Brechungsindex
162 ° (C=1, MeOH)
Löslichkeit
Practically insoluble in water, soluble in ethanol, sparingly soluble in methylene chloride.
pka
pKa 5.56±0.1 (Uncertain)
Aggregatzustand
Crystalline Powder
Farbe
White to off-white
Optische Aktivität
[α]22/D +170.0°, c = 1 in chloroform
Wasserlöslichkeit
SOLUBLE IN ACETIC ACID
Merck 
14,3590
BRN 
2229654
CAS Datenbank
471-53-4(CAS DataBase Reference)
EPA chemische Informationen
Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3.beta.,20.beta.)-(471-53-4)

Sicherheit

Kennzeichnung gefährlicher Xn
R-Sätze: 22-36
S-Sätze: 22-24/25
WGK Germany  3
RTECS-Nr. RK0180000
HS Code  29189900

Enoxolon Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R22:Gesundheitsschädlich beim Verschlucken.
R36:Reizt die Augen.

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Chemische Eigenschaften

white or greyish-white crystalline powder

Verwenden

An anti-inflammatory (topical).

Verwenden

antitussive, antiinflammatory, antibacterial

Verwenden

The aglycone of the triterpenoid Glyccyrrhizic acid.

Verwenden

glycyrrhetinic acid is anti-irritant, anti-allergenic, anti-inflammatory, skin-lightening, and smoothing properties are attributed to this ingredient, which is also a carrier. It is the organic compound derived from glycyrrhizic acid or shredded licorice roots.

Definition

ChEBI: A pentacyclic triterpenoid that is olean-12-ene substituted by a hydroxy group at position 3, an oxo group at position 11 and a carboxy group at position 30.

Anticancer Research

Glycyrrhetinic acid in combinationwith etoposide inhibits thetopoisomerase 2α and inducesapoptosis
Cai et al.(2017)

Anticancer Research

It was reported that GA at noncytotoxic concentrationshowed synergistic effect in combination with anticancer drug, etoposide (VP-16).Specifically, GA enhanced cytotoxicity through regulating topoisomerase II-αtargeted by etoposide. Also, GA sensitized the cells to etoposide through elevatingtopoisomerase II-α with a 2.4-fold rate at 12 h time point. From 12 to 48 h, GAhalved the expression of topoisomerase II-α and stimulated apoptosis, whichexhibited its antineoplastic effect. They reported that GA was more potentiallyeliminating the TNBC cells when compared with Glycyrrhizin Acid (Cai et al. 2017).

Enoxolon Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Enoxolon Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 295)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3194 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21672 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555
+86-021-57951555 jack.li@time-chemicals.com CHINA 1365 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30003 58
Chengdu Biopurify Phytochemicals Ltd.
18080483897
maggie@biopurify.com CHINA 2258 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768
sales@dolonchem.com CHINA 2972 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23980 58

471-53-4(Enoxolon)Verwandte Suche:


  • 3.beta.-Hydroxy-11-oxo-12-oleanen-30-oicacid
  • 3-beta-hydroxy-11-oxo-olean-12-en-30-oicaci
  • 3-beta-hydroxy-11-oxoolean-12-en-30-oicacid
  • 3-hydroxy-11-oxo-,(3.beta.,20.beta.)-Olean-12-en-29-oicacid
  • 3-hydroxy-11-oxo-,(3beta,20beta)-olean-12-en-29-oicaci
  • 3-Hydroxy-11-oxo-12-oleanen-30-oicacid
  • 3BETA-HYDROXY-11-OXO-18BETA, 20BETA-OLEAN-12-EN-29-OIC ACID
  • 3BETA-HYDROXY-11-OXO-18BETA-OLEAN-12-EN-30-OIC ACID
  • 3b-hydroxy-11-oxo-18b,20b-olean-12-en-29-oic acid
  • 3B-HYDROXY-11-OXO-18B-OLEAN-12-EN-30-OIC ACID
  • GLYCYRRHETINIC ACID
  • GLYCYRRHETIC ACID
  • GLYCYRRHETINIC ACID, 18B-
  • ENOXOLONE
  • ENOLOXONE
  • B-GLYCYRRHETINIC ACID
  • B-GLYCYRRNETINIC ACID
  • URALENIC ACID
  • 3β-Hydroxy-11-oxoolean-12-en-30-oic acid
  • 18-beta-Glycyrrhetinic acid, 98+%
  • Glycyrrhetinic
  • ENOXACIN GLUCONATE/18BETA-GLYCYRRHETINIC ACID
  • GLCYRRHETINIC ACID
  • CARBENOXOLONE(P)
  • Clycyrrhetinic Acid
  • 18-Beta-Glycyrrheticacid,Uralenicacid
  • 18β-Glycyrrhetic acid
  • Arthrodont
  • GM 1658
  • NSC 35347
  • Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3β,20β)-
  • Olean-12-en-30-oic acid, 3β-hydroxy-11-oxo- (8CI)
  • PO 12
  • STX 352
  • Subglycyrrhelinic acid
  • Uralenic acid (7CI)
  • GLYCERRHETINICACID
  • (3β,20b)-3-Hydroxy-11-oxo-olean-12-en-29-oic acid
  • 18-beta-GLYCYRRHETINIC ACID hplc
  • 18 BETA
  • 18b-Glycyrrhetic acid
  • 18beta-Glycyrrhetinic acid 97%
  • Enoxolone (18-β-glycyrrhetinic acid)
  • 3β-Hydroxy-11-oxoolean-12-en-30-olic acid
  • Glycyrrhetinate
  • 19β-Glycyrrhetinic acid
  • 20β-Glycyrrhetinic acid
  • 18-β-Glycyrrhetinic acid, 98+%
  • 18-beta-glycyrrheticacid
  • Enoxolone, 3β-Hydroxy-11-oxo-18β,20β-olean-12-en-29-oic acid
  • Aloe Vera, Freeze Dried Powder
  • Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3b,20b)-
  • (20S)-3β-Hydroxy-11-oxo-5α-olean-12-en-29-oic acid
  • GLYCYRRHETINIC ACID, 18B-(P)
  • Glycyrrhetinic acid ,98%
  • 18β-Glycyrrhetinic acid,3β-Hydroxy-11-oxo-18β,20β-olean-12-en-29-oic acid, Enoxolone
  • GLYCYRRHETINIC ACID, 18B-(SH)
  • 18 β-Glycyrrhetinic Acid / Enoxolone
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