4,4-Diethoxy-N,N-dimethyl-1-butanamine
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- CAS-Nr.
- 1116-77-4
- Englisch Name:
- 4,4-Diethoxy-N,N-dimethyl-1-butanamine
- Synonyma:
- 4,4-diethoxy-N,N-diMethylbutan-1-aMine;Zolmitriptan USP RC H;1-Butanamine,4,4-diethoxy-N,N-;Zolmitriptan Related Compound H;4,4-Diethoxy-N-Dimethylbutylamine;(4,4-DIETHOXY-BUTYL)-DIMETHYL-AMINE;4,4-DIETHOXY-N,N-DIMETHYLBUTANAMINE;Zolmitriptan USP Related Compound H;4-DiMethylaMinobutanol diethylacetal;4,4-DIETHOXY-N, N-DIMETHYL-BUTYLAMINE
- CBNumber:
- CB7176364
- Summenformel:
- C10H23NO2
- Molgewicht:
- 189.3
- MOL-Datei:
- 1116-77-4.mol
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4,4-Diethoxy-N,N-dimethyl-1-butanamine Eigenschaften
- Siedepunkt:
- 194-195C
- Dichte
- 0.844 g/mL at 25 °C(lit.)
- Brechungsindex
- n20/D 1.421(lit.)
- Flammpunkt:
- 158 °F
- storage temp.
- 2-8°C
- Löslichkeit
- Chloroform, Ethyl Acetate
- Aggregatzustand
- Oil
- pka
- 9.71±0.28(Predicted)
- Farbe
- Colourless to Pale Yellow
- CAS Datenbank
- 1116-77-4(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H318 |
Verursacht schwere Augenschäden. |
Schwere Augenschädigung |
Kategorie 1 |
Achtung |
![GHS hazard pictograms]() src="/GHS05.jpg" width="20" height="20" /> |
P280, P305+P351+P338, P310 |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
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4,4-Diethoxy-N,N-dimethyl-1-butanamine Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R41:Gefahr ernster Augenschäden.
R34:Verursacht Verätzungen.
R10:Entzündlich.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S16:Von Zündquellen fernhalten - Nicht rauchen.
Chemische Eigenschaften
Light yellow liquid
Verwenden
4,4-Diethoxy-N,N-dimethyl-1-butanamine is used in organic synthesis and pharmaceutical intermediates, it is an intermediate for Sumatriptan, Rizatriptan, Almotriptan, Zolmitriptan.
Application
4-Dimethylaminobutyraldehyde Diethyl Acetal (Zolmitriptan USP Related Compound H) is used in the preparation of N,N-Dimethyltryptamines, 5-HT1D receptor agonists, for medicinal treatments such as antimigraine drugs.
synthetische
4-Dimethylaminobutyraldehyde diethyl acetal synthesis: The reaction of 1-bromo-3-chloro propane and dimethylamine solution with PEG as a phase transfer catalyst, and obtained 3-dimethylamino-1-chloro propane. 3-dimethylamino-1-chloro propane reacted with magnesium and Grinard reagent was acquired. 4-Dimethylaminobutyraldehyde diethyl acetal is obtained by the reaction of Grinard reagent and triethyl orthoformate. The yield was 70.11%.
Synthesis Reference(s)
Tetrahedron Letters, 35, p. 2401, 1994
DOI: 10.1016/0040-4039(94)85230-8
4,4-Diethoxy-N,N-dimethyl-1-butanamine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4,4-Diethoxy-N,N-dimethyl-1-butanamine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 303)Lieferanten
1116-77-4()Verwandte Suche:
- N,N-DIMETHYL-4-AMINOBUTANAL DIETHYL ACETAL
- N, N-DIMETHYL-4,4-DIETHOXY-1-BUTANAMINE
- Zolmitriptan Related Compound H
- 4-(N,N-DIMETHYLAMINO)BUTANAL DIETHYL ACETAL
- 4-DIMETHYLAMINO BUTYRALDEHYDE DIETHYL ACETAL
- 4-DIMETHYLAMINO BUTANAL DIETHYL ACETAL
- (4,4-DIETHOXY-BUTYL)-DIMETHYL-AMINE
- 4,4-DIETHOXY-N,N-DIMETHYL-1-BUTANAMINE
- 4,4-DIETHOXY-N,N-DIMETHYLBUTANAMINE
- 4,4-DIETHOXY-N, N-DIMETHYL-BUTYLAMINE
- 1-BUTANAMINE 4,4-DIETHOXY-N,N-DIMETHYL
- 1-Butanamine, 4,4-diethoxy-N,N-dimethyl- S
- 4,4-Diethoxy-N,N-dimethyl-1-butanamine(DDBA)
- 1-Butanamine,4,4-diethoxy-N,N-
- 4,4-diethoxy-N,N-dimethyl-butylamine (intermediate of zolmitriptan and sumatriptan)
- 4-(N,N-DIMETHYLAMINO)BUTANAL DIETHYL ACETAL(FOR ZOLMITRIPTAN AND OTHER TRIPTANS)
- 4-(N,N-DIMETHYLAMINO)-BUTYRALDEHYDE DIETHYL ACETAL
- 4-N,N-DIMETHYLAMINOBUTANAL DIETHYL ACETAL (FOR SUMATRIPTAN, RIZATRIPTAN, ZOLMITRIPTAN)
- 4-N,N-dimethylaminobutanal diethyl acetal ( For Triptans )
- 4,4-DIETHOXY-N,N-DIMETHYL BUTYLAMINE,GC 96+%
- 4-DimethylamineButyaldehydeDimethylAcetal(ForSumatriptan)
- 4-Dimethylamine butyaldehyde dimethyl acetal
- N,N-diethylamino-butyraldehyde diethyl acetal
- 4,4-Diethoxy-N-Dimethylbutylamine
- 4-(N,N-Dimethylamino)butyaldehyde diethyl acetal
- 1-(N,N-Dimethylamino)-4,4-diethoxybutane
- Zolmitriptan USP RC H
- 4,4-Diethoxy-N,N-diMethyl-1-butanaMine, 97.5%
- 4-DiMethylaMinobutanol diethylacetal
- 4,4-diethoxy-N,N-dimethyl-1-But·Namine
- 4,4-Diethoxy-N,N-dimethyl-1-butanamine 1116-77-4
- 1116-77-4 4,4-Diethoxy-N,N-dimethyl-1-butanamine
- 4,4-Dimethylaminobutyraldehyde diethylacetal
- Zolmitriptan USP Related Compound H
- 4-(Dimethylamino)butyraldehydeDiethylAcetal>
- Zolmitriptan Impurity 10(Zolmitriptan USP RC H)
- 4,4-Diethoxy-N,N-dimethyl-1-l-butanamine
- 4-(N,N-Dimethylamino) butane ditheyl acetal
- 4-Dimethylaminobutyraldehyde Diethyl Acetal/Zolmitriptan
USP RC H
- 4-Dimethylamino Butanal Diethyl AcetalQ: What is
4-Dimethylamino Butanal Diethyl Acetal Q: What is the CAS Number of
4-Dimethylamino Butanal Diethyl Acetal Q: What is the storage condition of
4-Dimethylamino Butanal Diethyl Acetal Q: What are the applications of
4-Dimethylamino Butanal Diethyl Acetal
- Zolmitriptan Related Compound H (4,4-Diethoxy-N,N-dimethylbutan-1-amine) (1727097)
- 4,4-diethoxy-N,N-diMethylbutan-1-aMine
- 1116-77-4
- 116-77-4
- CH32NCH23CHOCH2CH32
- C10H23NO2
- C9 to C10
- Amines
- Building Blocks
- Nitrogen Compounds
- Organic Building Blocks
- Other Products
- API intermediates
- Intermediates of Rizatriptan
- Amines
