RAC 8-HYDROXY EFAVIRENZ

205754-33-2

CAS-Nr.: 205754-33-2

Englisch Name:: RAC 8-HYDROXY EFAVIRENZ

Synonyma:: 8-HydroxyEfavirenz;RAC 8-HYDROXY EFAVIRENZ;Efavirenz Impurity 11(8-Hydroxy Efavirenz);(4S)-6-chloro-4-(2-cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one;6-Chloro-4-(cyclopropyl-d4-ethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one;2H-3,1-Benzoxazin-2-one,6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-;2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-;8-Hydroxy EfavirenzQ: What is 8-Hydroxy Efavirenz Q: What is the CAS Number of 8-Hydroxy Efavirenz Q: What is the storage condition of 8-Hydroxy Efavirenz Q: What are the applications of 8-Hydroxy Efavirenz

CBNumber:: CB7501021

Summenformel:: C14H9ClF3NO3

Molgewicht:: 331.67

MOL-Datei:: 205754-33-2.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 29

RAC 8-HYDROXY EFAVIRENZ Eigenschaften

Schmelzpunkt:: 144-154°C

Siedepunkt:: 373.6±42.0 °C(Predicted)

Dichte: 1?+-.0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: Acetonitrile: soluble; DMSO: soluble; Methanol: soluble

Aggregatzustand: A solid

pka: 7.18±0.40(Predicted)

Sicherheit

RAC 8-HYDROXY EFAVIRENZ Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz . 8-hydroxy Efavirenz is formed when efavirenz is metabolized by the cytochrome P450 (CYP) isoform CYP2B6. It induces apoptosis in rat primary hippocampal neurons and loss of dendritic spines in rat primary hippocampal neuronal cultures when used at a concentration of 0.01 μM.

Chemische Eigenschaften

Off-White Solid

Verwenden

A labellebed metabolite of Efavirenz, a nonnucleoside HIV-1 reverse transcriptase inhibitor

RAC 8-HYDROXY EFAVIRENZ Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

RAC 8-HYDROXY EFAVIRENZ Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 29)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
Guangzhou PI PI Biotech Inc	+86-020-81716320 +86-13602409664	Sales@pipitech.com	China	3635	55
Shanghai Devinchem Ltd	027-65318838 13646286950	sales@devinchem.com	China	2984	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	94838	76
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15421	60
BOC Sciences	16314854226	info@bocsci.com	United States	9926	65
Shanghai SuperLan Chemcial Technique Centre	021-2022843681 15618226720	chaolaichem@foxmail.com	China	6870	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	55791	58
Guangzhou Dreampharm Biotechnology Co., Ltd.	17825480238	3008233717@qq.com	China	9844	12

RAC 8-HYDROXY EFAVIRENZ
8-HydroxyEfavirenz
6-Chloro-4-(cyclopropyl-d4-ethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
(4S)-6-chloro-4-(2-cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
Efavirenz Impurity 11(8-Hydroxy Efavirenz)
2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-
8-Hydroxy EfavirenzQ: What is 8-Hydroxy Efavirenz Q: What is the CAS Number of 8-Hydroxy Efavirenz Q: What is the storage condition of 8-Hydroxy Efavirenz Q: What are the applications of 8-Hydroxy Efavirenz
2H-3,1-Benzoxazin-2-one,6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-
205754-33-2
Metabolites
Non-nucleoside Reverse Transcriptase
Pharmaceuticals
Intermediates & Fine Chemicals
Isotope Labeled Compounds