2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)1H-indol- 5-ol

2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)1H-indol- 5-ol Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

PP242 hydrate has been used:

• as a mammalian target of rapamycin (mTOR) inhibitor to study its effects on rat fibroblast mTOR complex 1 and 2 (mTORC1 & 2) signaling
• as an mTOR inhibitor to treat mouse embryonic fibroblasts (MEF) and cumulus cells (CCs) to study its effects on reactivation of embryonic nucleoli and ribosome biogenesis
• as a target of rapamycin (TOR) kinase inhibitor for the treatment of Arabidopsis to study its effects against Fusarium graminearum infection

Biochem/physiol Actions

PP242 is a potent and selective mTOR inhibitor. PP242 is a first selective inhibitor that targets ATP domain of mTOR.

2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)1H-indol- 5-ol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)1H-indol- 5-ol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
SynphaBase AG	--	info@synphabase.ch	Switzerland	628	60
Riedel-de Haen AG	--		United States	6825	87

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• 2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)1H-indol- 5-ol
• PP242 hydrate
• Heterocyclic Building Blocks