2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)1H-indol- 5-ol C화학적 특성, 용도, 생산
용도
PP242 hydrate has been used:
as a mammalian target of rapamycin (mTOR) inhibitor to study its effects on rat fibroblast mTOR complex 1 and 2 (mTORC1 & 2) signaling
as an mTOR inhibitor to treat mouse embryonic fibroblasts (MEF) and cumulus cells (CCs) to study its effects on reactivation of embryonic nucleoli and ribosome biogenesis
as a target of rapamycin (TOR) kinase inhibitor for the treatment of Arabidopsis to study its effects against Fusarium graminearum infection
Biochem/physiol Actions
PP242 is a potent and selective mTOR inhibitor. PP242 is a first selective inhibitor that targets ATP domain of mTOR.
2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)1H-indol- 5-ol 준비 용품 및 원자재
원자재
준비 용품
2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)1H-indol- 5-ol 공급 업체
