Growth hormone releasing peptide
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- CAS-Nr.
- 87616-84-0
- Englisch Name:
- Growth hormone releasing peptide
- Synonyma:
- GHRP-6;Growth;GHRP-6 ACETATE;gonadorel;sk&f110679;HWAWFK-NH2;GHRP-6220vial;GHRP-6 powder;GRHP-6 Acetate;[HIS1, LYS6]-GHRP
- CBNumber:
- CB8421540
- Summenformel:
- C46H56N12O6
- Molgewicht:
- 873.01
- MOL-Datei:
- 87616-84-0.mol
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Growth hormone releasing peptide Eigenschaften
- Schmelzpunkt:
- >160o C (Dec.)
- Siedepunkt:
- 1407.0±65.0 °C(Predicted)
- Dichte
- 1.333±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- Löslichkeit
- Methanol (Slightly), Water (Slightly)
- Aggregatzustand
- Solid
- pka
- 13.42±0.46(Predicted)
- Farbe
- White to Off-White
- Sequenz
- is-D-Trp-Ala-Trp-D-Phe-Lys-NH2|H-His-D-Trp-Ala-Trp-D-Phe-Lys-NH2
- InChIKey
- WZHKXNSOCOQYQX-FUAFALNISA-N
- SMILES
- C(N)(=O)[C@H](CCCCN)NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)[C@H](CC1C2=C(C=CC=C2)NC=1)NC(=O)[C@H](C)NC(=O)[C@@H](CC1C2=C(C=CC=C2)NC=1)NC(=O)[C@H](CC1N=CNC=1)N
- CAS Datenbank
- 87616-84-0(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
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Growth hormone releasing peptide Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Growth hormone-releasing peptides (GHRPs) are synthetic, non-natural peptides endowed with potent stimulatory effects on somatotrope secretion in animals and humans. They have no structural homology with GHRH and act via specific receptors present either at the pituitary or the hypothalamic level both in animals and in humans.
Verwenden
Growth hormone releasing peptide-6 can promote the secretion of growth hormone, regulate food intake, increase weight, and promote animal growth.
Mechanism of action
Growth hormone releasing peptide is generally accepted that GHRPs stimulate the release of GH by acting at the level of the pituitary through a receptor different to that for the endogenous GH-releasing hormone (GHRH). In addition, it has been reported that there are specific binding sites for these peptides in the hypothalamus and that systemic administration of GHRPs increases the expression of the immediate early gene c-fos in a subpopulation of hypothalamic neurons.
Nebenwirkungen
Carpal tunnel syndrome.Increased insulin resistance.
Type 2 diabetes.
Swelling in the arms and legs (edema)
Joint and muscle pain.
For men, enlargement of breast tissue (gynecomastia).
Increased risk of certain cancers.
Physiological effects
Growth hormone releasing peptide (GHRP) is a cyclase inhibitor that blocks the release of endogenous growth hormone.The peptide acts on both igf-i and somatotrophs, with receptor activity in the hypothalamus.GHRP can be used to increase body weight and control obesity.It has been shown to stimulate cell division and inhibit apoptosis in vitro.
Solubility in water
It is recommended to reconstitute the lyophilized growth hormone releasing peptide in sterile 18MΩ-cm H
2O not less than 100 μg/ml, which can then be further diluted to other aqueous solutions.
Growth hormone releasing peptide Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Growth hormone releasing peptide Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 261)Lieferanten
87616-84-0()Verwandte Suche:
- D-TRP7,ALA8,D-PHE10]-A-MELANOCYTESTIMULATINGHORMONEAMIDEFRAGMENT6-11
- (2S)-6-amino-2-[[2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(3H-imidazol-4-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenyl-propanoyl]amino]hexanamide
- Growth hormone releasing peptide
- (D-trp7,ala8,D-phe10)-A-melanocyte*stimulating ho
- (D-TRP7,ALA8,D-PHE10)-A-MELANOCYTE*STIMU LATING HORM
- [d-trp7, ala8, d-phe10]-α-melanocyte stimulating hormone amide fragment 6-11
- Growth hormone-releasing peptide【synthetic】
- L-His-D-Trp-L-Ala-L-Trp-D-Phe-L-Lys-NH2
- [His1, Lys6] - GHRP, GHRP- 6
- alpha-melanotropin, fragment 6-11, [D-Trp7,Ala8,D-Phe10]
- (D-Trp7,Ala8,D-Phe10)-a-MSH (6-11) aMide
- L-LysinaMide,L-histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-
- (D-Trp7,Ala8,D-Phe10)-α-MSH (6-11) amide, GHRP-6
- sk&f110679
- [D-TRP7, ALA8, D-PHE10]-ALPHA-MELANOCYTE STIMULATING HORMONE (6-11) AMIDE
- [D-TRP7,ALA8,D-PHE10]-ALPHA-MELANOCYTE STIMULATING HORMONE FRAGMENT 6-11 AMIDE
- (D-TRP7,ALA8,D-PHE10)-ALPHA-MSH (6-11) AMIDE
- [HIS1, LYS6]-GHRP
- HIS-D-TRP-ALA-TRP-D-PHE-LYS-NH2
- H-HIS-D-TRP-ALA-TRP-D-PHE-LYS-NH2
- GROWTH HORMONE RELEASING PEPTIDE-6
- GROWTH HORMONE RELEASING PROTEIN-6
- HWAWFK-NH2
- (S)-6-Amino-2-((2R,5S,8S,11R,14S)-5,11-bis((1H-indol-3-yl)methyl)-14-amino-2-benzyl-15-(1H-imi
- High Purity Ghrp-6 Peptide For Lean Muscle Mass CAS NO.87616-84-0 CAS NO.87616-84-0
- L-Histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide
- GHRP-6220vial
- GHRP-6220vial(5mg/vial)
- (2S)-6-amino-2-[[2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamide
- GHRP-6(Growth hormone releasing peptide)
- Hexapeptide-2/GHRP-6
- L-Histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide Acetate Salt
- GHRP-6 powder
- GH-Releasing peptide
- Pharmaceutical Grade Peptides Myostatin Gdf8 for Bodybuilding
- Peptide Powder Ghrp-6 Ghrp 6 for Injection
- Growth hormone releasing peptide USP/EP/BP
- (D-Trp7,Ala8,D-Phe10)-α-MSH (6-11) amide
- Peptides G-H-′ R-′ P-6
- (D-Trp7,Ala8,D-Phe10)-α-MSH (6-11) amide, GHRP-6
- Growth
- GHRP-6
- GHRP-6 ACETATE
- GRHP-6 Acetate
- GHRP-6 acetate salt
- gonadorel
- (D-Trp?,Ala?,D-Phe??)-α-MSH (6-11) amide
- 87616-84-0
- C50H64N12O6
- BioChemical
- Cell Signaling and Neuroscience
- Cell Biology
- Pituitary Hormones
- Cytokines, Growth Factors and Hormones
- Hormones
- Melanocyte Stimulating Hormone (MSH)
- Peptide
- GHRP6
