CCG-232601

1922099-21-5

CAS-Nr.: 1922099-21-5

Englisch Name:: CCG-232601

Synonyma:: CCG-232601;CCG-232601 (CCG232601);N-(4-chlorophenyl)-5,5-difluoro-1-[3-(4-pyridinyl)benzoyl]-3-piperidinecarboxamide;3-Piperidinecarboxamide, N-(4-chlorophenyl)-5,5-difluoro-1-[3-(4-pyridinyl)benzoyl]-

CBNumber:: CB84665922

Summenformel:: C24H20ClF2N3O2

Molgewicht:: 455.88

MOL-Datei:: 1922099-21-5.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 10

CCG-232601 Eigenschaften

Siedepunkt:: 683.1±55.0 °C(Predicted)

Dichte: 1.39±0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml

Aggregatzustand: A crystalline solid

pka: 13.69±0.70(Predicted)

Sicherheit

CCG-232601 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

CCG-232601 is an inhibitor of the Rho/MRTF/SRF transcriptional pathway and a derivative of CCG-203971 . CCG-232601 inhibits MRTF-dependent transcription in HEK293T cells (IC₅₀ = 0.55 μM in a luciferase reporter assay). It also reduces expression of α-smooth muscle actin (α-SMA) in TGF-β-stimulated human dermal fibroblasts to 31% of control when used at a concentration of 10 μM. CCG-232601 (50 mg/kg) inhibits increases in dermal thickness and hydroxyproline content in a mouse model of dermal fibrosis induced by bleomycin .

CCG-232601 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

CCG-232601 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 10)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd	15317229551	15151849396@163.com	China	997	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24131	58
Nanjing Tengyi Biotechnology Co., Ltd	025-58851786 17714337195	sales@tybiochem.com	China	4257	58

CCG-232601
CCG-232601 (CCG232601)
3-Piperidinecarboxamide, N-(4-chlorophenyl)-5,5-difluoro-1-[3-(4-pyridinyl)benzoyl]-
N-(4-chlorophenyl)-5,5-difluoro-1-[3-(4-pyridinyl)benzoyl]-3-piperidinecarboxamide
1922099-21-5