L371,257

162042-44-6

CAS-Nr.: 162042-44-6

Englisch Name:: L371,257

Synonyma:: 257;L-371;L371,257;L371,257,L 371,257;1-[1-[4-(1-acetylpiperidin-4-yl)oxy-2-methoxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one;1-[4-[(1-Acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-(2-oxo-2H-3,1-benzoxazin-1(4H)-yl)piperidine;2H-3,1-Benzoxazin-2-one, 1-[1-[4-[(1-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-piperidinyl]-1,4-dihydro-

CBNumber:: CB8850593

Summenformel:: C28H33N3O6

Molgewicht:: 507.58

MOL-Datei:: 162042-44-6.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 31

L371,257 Eigenschaften

Siedepunkt:: 728.9±60.0 °C(Predicted)

Dichte: 1.282±0.06 g/cm3(Predicted)

storage temp.: Store at RT

Löslichkeit: Soluble to 10 mM in DMSO with gentle warming

Aggregatzustand: Powder

pka: 0.73±0.20(Predicted)

Sicherheit

L371,257 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

L-371,257 is a potent antagonist of oxytocin-induced contractions of the rat uterus in vitro and in vivo and has significant oral bioavailability in rats.

Biologische Aktivität

Potent, high affinity human oxytocin (OT) receptor antagonist (K i = 4.6 nM) that displays > 800-fold selectivity over human arginine vasopressin receptors V 1a and V 2 . Antagonizes oxytocin-induced contractions in isolated rat uterine tissue (pA 2 = 8.44) and in anesthetised rats following intravenous and intraduodenal administration. Orally active.

L371,257 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

L371,257 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 31)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Beijing Solarbio Science & Tecnology Co., Ltd.	010-50973130 4009686088	3193328036@qq.com	China	29797	68
Hebei Weite Medical Technology Co., Ltd	13180081292	contact@wetogethermed.com	China	7267	58
Nantong Hi-Future Biotechnology Co., Ltd	18051384581	sales@chemhifuture.com	China	2996	58
Shanghai Universal Biotech Co.,Ltd	18768175414	gaojun@univ-bio.com	China	24998	58

162042-44-6()Verwandte Suche:

1-Benzyl-N-phenylpiperidin-4-amin 2,4-Dihydroxybenzamid

L371,257
1-[4-[(1-Acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-(2-oxo-2H-3,1-benzoxazin-1(4H)-yl)piperidine
1-[1-[4-(1-acetylpiperidin-4-yl)oxy-2-methoxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
2H-3,1-Benzoxazin-2-one, 1-[1-[4-[(1-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-piperidinyl]-1,4-dihydro-
257
L-371
L371,257,L 371,257
162042-44-6
C28H33N3O6