2'-O-Methylcytidine

2'-O-Methylcytidine Struktur
2140-72-9
CAS-Nr.
2140-72-9
Englisch Name:
2'-O-Methylcytidine
Synonyma:
4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one;OMe-rC;2'-OMe-C;2'-OMe-rC;2'-OMe-Cr;2'-OMe Cytidine;2'-O-METHYLCYTIDINE;2'-O-Methylcytidine;2'-O-Methyl-D-cytidine;2'-O-Methylcytidine>
CBNumber:
CB9324099
Summenformel:
C10H15N3O5
Molgewicht:
257.24
MOL-Datei:
2140-72-9.mol

2'-O-Methylcytidine Eigenschaften

Schmelzpunkt:
252-253 C
Siedepunkt:
506.0±60.0 °C(Predicted)
Dichte
1.68±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
Löslichkeit
Soluble in DMSO.
pka
13.37±0.70(Predicted)
Aggregatzustand
Powder
Farbe
White to Off-white
InChI
InChI=1S/C10H15N3O5/c1-17-8-7(15)5(4-14)18-9(8)13-3-2-6(11)12-10(13)16/h2-3,5,7-9,14-15H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,9-/m1/s1
InChIKey
RFCQJGFZUQFYRF-ZOQUXTDFSA-N
SMILES
OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](OC)[C@@H]1O
CAS Datenbank
2140-72-9(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher Xi
R-Sätze: 36/37/38
S-Sätze: 26-36-24/25
WGK Germany  3
HS Code  29349990

2'-O-Methylcytidine Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Beschreibung

2'-O-Methylcytidine is a nucleoside with a hydroxyl group on the 2' carbon, making it an effective viral replication inhibitor. 2'-O-Methylcytidine is also metabolized by nucleotide salvage pathways and may be able to bind to the response element on DNA, which could inhibit protein synthesis in cancer cells. It is an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50 = 3.8 μM). It inhibits HCV replication in a replicon assay (IC50 = 21.2 μM).

Chemische Eigenschaften

White powder

Verwenden

2'-O-Methylcytidine is used in the preparation of nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase.

2'-O-Methylcytidine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


2'-O-Methylcytidine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 229)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Yunbio Tech Co.,Ltd.
+86-010-60605551 +86-18046518538
yunbiochem@126.com China 321 58
LEAPCHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 43348 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652
info@fdachem.com China 7845 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806
sales@capotchem.com China 29797 60
career henan chemical co
+86-0371-86658258
sales@coreychem.com China 29914 58
Nanjing Baifuli Technology Co., Ltd.
+86-15335185688
sales@unisyn.cn CHINA 332 58
Hubei xin bonus chemical co. LTD
86-13657291602
linda@hubeijusheng.com CHINA 22968 58
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873
sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 63711 58

2140-72-9()Verwandte Suche:


  • 2'-OMe-C
  • 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-3-methoxy-5-methylol-tetrahydrofuran-2-yl]pyrimidin-2-one
  • 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidin-2-one
  • 4-azanyl-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxy-oxolan-2-yl]pyrimidin-2-one
  • 2'-OMe Cytidine
  • 4-aMino-1-[(2R,3R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)-3-Methoxyoxolan-2-yl]-1,2-dihydropyriMidin-2-one
  • 2'-O-Methylcytidine, >=99%
  • 2'-O-METHYLCYTIDINE
  • 2''-(O-METHYL)-CYTIDINE, HPLC PURIFIED, 98% PURE WITH HPLC UV CHROMATOGRAM
  • 2'-O-Methylcytidineanhydrous
  • 2'-O-Methyl-D-cytidine
  • 2'-O-Methylcytidine, >98.0%(HPLC)
  • 2'-O-Methylcytidine>
  • 2'-OMe-rC
  • 2'-O-Methylcytidine USP/EP/BP
  • 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-1,2-dihydropyrimidin-2-one
  • 2'-OMe-Cr
  • 2’-O-Methyl cytidine, RNA nucleoside Cm
  • 4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one
  • OMe-rC
  • 2'-O-Methylcytidine
  • 2140-72-9
  • Nucleosides, Nucleotides, Oligonucleotides
  • Nucleoside Analogs
  • BioChemical
  • Biochemicals and Reagents
  • Bases & Related Reagents
  • Carbohydrates & Derivatives
  • Heterocycles
  • Nucleotides
  • Nucleosides, Nucleotides, Oligonucleotides
  • Biochemicals and Reagents
  • Nucleoside Analogs
  • Nucleosides
  • Modified(deoxy)nucleoside
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