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4-(Phthalimide)cyclohexanol

CAS No.
104618-31-7
Chemical Name:
4-(Phthalimide)cyclohexanol
Synonyms
4-(Phthalimide)cyclohexanol;2-(4-Hydroxycyclohexyl)isoindol-1,3-dione;2-(4-Hydroxycyclohexyl)isoindoline-1,3-dione;1H-Isoindole-1,3(2H)-dione,2-(4-hydroxycyclohexyl);2-(4-Hydroxycyclohexyl)-1H-isoindole-1,3(2H)-dione
CBNumber:
CB01075076
Molecular Formula:
C14H15NO3
Molecular Weight:
245.27
MDL Number:
MOL File:
104618-31-7.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:42
Product description Number Pack Size Price
4-(PHTHALIMIDE)CYCLOHEXANOL 95.00% CHM0382883 5MG $503.34
4-(Phthalimide)cyclohexanol 95% AA008Y47 1g $515
2-(4-Hydroxycyclohexyl)isoindoline-1,3-dione 104618317 5g $1038.8
4-(Phthalimide)cyclohexanol 95% AA008Y47 250mg $246
2-(4-hydroxycyclohexyl)isoindoline-1,3-dione 95%+ CM133673 1g $262
More product size

4-(Phthalimide)cyclohexanol Properties

Boiling point 410.1±38.0 °C(Predicted)
Density 1.365
storage temp. Sealed in dry,Room Temperature
pka 14.99±0.40(Predicted)

4-(Phthalimide)cyclohexanol price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation CHM0382883 4-(PHTHALIMIDE)CYCLOHEXANOL 95.00% 104618-31-7 5MG $503.34 2021-12-16 Buy
aablocks AA008Y47 4-(Phthalimide)cyclohexanol 95% 104618-31-7 1g $515 2021-12-16 Buy
Alichem 104618317 2-(4-Hydroxycyclohexyl)isoindoline-1,3-dione 104618-31-7 5g $1038.8 2021-12-16 Buy
aablocks AA008Y47 4-(Phthalimide)cyclohexanol 95% 104618-31-7 250mg $246 2021-12-16 Buy
Chemenu CM133673 2-(4-hydroxycyclohexyl)isoindoline-1,3-dione 95%+ 104618-31-7 1g $262 2021-12-16 Buy
Product number Packaging Price Buy
CHM0382883 5MG $503.34 Buy
AA008Y47 1g $515 Buy
104618317 5g $1038.8 Buy
AA008Y47 250mg $246 Buy
CM133673 1g $262 Buy

4-(Phthalimide)cyclohexanol Chemical Properties,Uses,Production

Synthesis

N-Carbethoxyphthalimide

22509-74-6

4-Aminocyclohexanol

6850-65-3

4-(Phthalimide)cyclohexanol

104618-31-7

General procedure for the synthesis of 2-(4-hydroxycyclohexyl)isoindole-1,3-dione from N-ethoxycarbonylphthalimide and 4-aminocyclohexanol: 4-aminocyclohexanol (2.627 g, 22.81 mmol) and 1,3-dioxo-1,3-dihydroisoindole-2-carboxylic acid ethyl ester (5 g, 22.81 mmol) were placed in large test tubes using a heat gun until both were completely melted and continued heating for 5 minutes. After completion of the reaction, the resulting solution was allowed to cool to room temperature and a solid was formed. The solid product was transferred to a flask, dissolved in dichloromethane (CH2Cl2) and purified by column chromatography (75% ethyl acetate/hexane) to afford 4.57 g of 2-(4-hydroxycyclohexyl)isoindole-1,3-dione in 81% yield.LCMS (m/z): [M+H+MeCN]+ = 287.1.

References

[1] Patent: US2008/269193, 2008, A1. Location in patent: Page/Page column 33
[2] Patent: WO2013/13188, 2013, A1. Location in patent: Paragraph 00486
[3] Patent: US9416132, 2016, B2. Location in patent: Page/Page column 183; 184
[4] Journal of medicinal chemistry, 1993, vol. 36, # 13, p. 1918 - 1919

85-44-9
27489-62-9
104618-31-7
Synthesis of 4-(Phthalimide)cyclohexanol from Phthalic anhydride and trans-4-Aminocyclohexanol

4-(Phthalimide)cyclohexanol Preparation Products And Raw materials

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2-(4-Hydroxycyclohexyl)-1H-isoindole-1,3(2H)-dione 2-(4-Hydroxycyclohexyl)isoindol-1,3-dione 4-(Phthalimide)cyclohexanol 2-(4-Hydroxycyclohexyl)isoindoline-1,3-dione 1H-Isoindole-1,3(2H)-dione,2-(4-hydroxycyclohexyl) 104618-31-7