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trans-4-Aminocyclohexanol

CAS No.
27489-62-9
Chemical Name:
trans-4-Aminocyclohexanol
Synonyms
(1r,4r)-4-aminocyclohexanol;(1s,4s)-4-Aminocyclohexanol;trans-4-aminocyclohexan-1-ol;AURORA KA-7506;trans-4-AminocycL;TIMTEC-BB SBB005825;trans-4-Aminocyclohe;Ambroxol Impurity 36;4-(E)-aMino cyclohexano;Ammonia bromine AMB - F
CBNumber:
CB7139383
Molecular Formula:
C6H13NO
Molecular Weight:
115.17
MDL Number:
MFCD00067698
MOL File:
27489-62-9.mol
Last updated:2024-04-08 17:36:13

trans-4-Aminocyclohexanol Properties

Melting point 108-113°C
Boiling point 127 °C / 14mmHg
Density 0.9837 (rough estimate)
refractive index 1.4713 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Crystals
pka 15.12±0.40(Predicted)
color White to almost white
Water Solubility Soluble in water.
Sensitive Hygroscopic
LogP -0.4
CAS DataBase Reference 27489-62-9(CAS DataBase Reference)
FDA UNII D6E7B62984

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314-H318
Precautionary statements  P260-P264-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P405-P501-P260h-P301+P330+P331-P303+P361+P353-P305+P351+P338-P501a
Hazard Codes  Xi,C,Xn
Risk Statements  36/37/38-34-41-37/38-22
Safety Statements  26-37/39-45-36/37/39-39
RIDADR  3259
Hazard Note  Irritant
HazardClass  8
PackingGroup 
HS Code  29221990
NFPA 704
1
3 0

trans-4-Aminocyclohexanol price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A1160 trans-4-Aminocyclohexanol >98.0%(GC) 27489-62-9 25g $33 2024-03-01 Buy
TCI Chemical A1160 trans-4-Aminocyclohexanol >98.0%(GC) 27489-62-9 500g $363 2024-03-01 Buy
Alfa Aesar B22365 trans-4-Aminocyclohexanol 98+% 27489-62-9 5g $42.65 2024-03-01 Buy
Alfa Aesar B22365 trans-4-Aminocyclohexanol 98+% 27489-62-9 25g $138.65 2024-03-01 Buy
Alfa Aesar B22365 trans-4-Aminocyclohexanol 98+% 27489-62-9 100g $408.65 2024-03-01 Buy
Product number Packaging Price Buy
A1160 25g $33 Buy
A1160 500g $363 Buy
B22365 5g $42.65 Buy
B22365 25g $138.65 Buy
B22365 100g $408.65 Buy

trans-4-Aminocyclohexanol Chemical Properties,Uses,Production

Description

Trans-4-Aminocyclohexanol is also named as Cis-4-Aminocyclohexanol. It was a medical intermediate of ambroxol, which is used in the treatment of respiratory diseases associated with viscid or excessive mucus.1 It is used as a raw material in organic synthesis, such as in the synthesis of N-substituted 7-azabicyclo [2.2.1] hepatanes, which are good substrates for microbial oxidation of unactivated carbons by B.bassiana.2

Reference

  1. Y. Jian, Improved Process of the Synthesis of Trans-4-aminocyclohexanol, Fine Chemicals, 2000, vol. 2
  2. H. F. Olivo, M. S. Hemenway, M. H. Gezginci, Synthesis and Microbial Hydroxylation of Some Azabicycloalkanes, Tetrahedron Letters, 1998, vol. 39, pp. 1309-1312

Chemical Properties

white to light yellow crystal powder

Uses

trans-4-Aminocyclohexanol is used as raw material in organic synthesis and is an important intermediate in the synthesis of drugs such as Ambroxol hydrochloride. It can react with butyric acid-(2-chloro-ethyl ester) to get butyric acid 4-amino-cyclohexyl ester. This reaction needs catalytic agent Aspergillus niger lipase and solvent 2-methyl-butan-2-ol.

Uses

trans-4-aminocyclohexanol be used as organic intermediates.

Global( 533)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5993 58
airuikechemical co., ltd.
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Capot Chemical Co.,Ltd.
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Shanghai Daken Advanced Materials Co.,Ltd
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Henan Tianfu Chemical Co.,Ltd.
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Hangzhou FandaChem Co.,Ltd.
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Jiangsu Qingquan Chemical Co., Ltd.
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ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
NINGBO INNO PHARMCHEM CO., LTD.
13867897135 sales@nbinno.com CHINA 925 58

View Lastest Price from trans-4-Aminocyclohexanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Trans-4-aminocyclohexanol pictures 2024-04-08 Trans-4-aminocyclohexanol
27489-62-9
US $0.00-0.00 / Kg 1Kg 99.9% 200tons airuikechemical co., ltd.
trans-4-Aminocyclohexanol pictures 2023-10-09 trans-4-Aminocyclohexanol
27489-62-9
US $0.00 / kg 1kg 0.99 20tons Hebei Yanxi Chemical Co., Ltd.
trans-4-Aminocyclohexanol pictures 2022-10-14 trans-4-Aminocyclohexanol
27489-62-9
US $0.00-0.00 / KG 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.
trans-4-Aminocyclohexanol,97% trans-4-Aminocyclohexanol Trans-4-Amimocyclohexanol Cyclohexanol, 4-amino-, trans- (1α)-4β-Aminocyclohexanol trans-4-Aminocyclohexanol ,99% trans-4-Aminocyclohe Trans-4-aMniocyclohexanol 4-trans-Hydroxycyclohexylamine 4-(E)-aMino cyclohexano Trans-4-aMino cyclohexanol (TACH) trans-4-Aminocyclohexanol The trans-aminocyclohexanol trans-1-amino-4-cyclohexanol TIMTEC-BB SBB005825 TRANS-4-AMINO-1-HYDROXYCYCLOHEXANE AMINOCYCLOHEXANOL(TRANS-4) 4-Trans amino cyclohexanol trans-4-Aminocyclohexanol, 98+% AURORA KA-7506 trans-4-hydroxycyclohexylamine trans-4-Aminocyclohexanol 97% Trans-4-Aminocyclohexanol ( For Ambroxol Hcl ) trans-4-AminocycL Ambroxol Hydrochloride Impurity 4 trans-4-Aminocyclohexanol> Ammonia bromine AMB - F Ambroxol Impurity 36 Trans-4-Amonocyclohexanol Trans-4-amino cyclohexyl phenol (1r,4r)-4-aminocyclohexanol (1s,4s)-4-Aminocyclohexanol trans-4-aminocyclohexan-1-ol Anti-4-amino cyclohexanol rans-4-Aminocyclohexanol (1r,4r)-4-aminocyclohexan-1-ol (1r,4r)-4-aminocyclohexanol/trans-4-Aminocyclohexanol 27489-62-9 50910-58-5 27489-63-9 chiral Amines blocks BuildingBlocks Ambroxol