ChemicalBook >> CAS DataBase List >>3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine
3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine
- CAS No.
- 306387-90-6
- Chemical Name:
- 3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine
- Synonyms
- KAAD Cyclopamine,KAADCyclopamine;3-Keto-N-aMinoethyl-N'-aMinocaproyldihydrocinnaMoyl CyclopaMine, >80%;Benzenepropanamide, N-[6-[[2-[(3'R,3'aS,6'S,6aS,6bS,7'aR,2'R,11aS,11bR)-1,2,3,3',3'a,4,5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-octadecahydro-3',6',10,11b-tetramethyl-3-oxospiro[9H-benzo[a]fluorene-9,2'(4'H)-furo[3,2-b]pyridin]-4'-yl]ethyl]amino]-6-oxohexyl]-
- CBNumber:
- CB01175752
- Molecular Formula:
- C44H63N3O4
- Molecular Weight:
- 697.999
- MDL Number:
- MFCD03425585
- MOL File:
- 306387-90-6.mol
Last updated:2023-06-08 09:01:53
| Boiling point | 875.6±65.0 °C(Predicted) |
|---|---|
| Density | 1.15±0.1 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| solubility | Chloroform: Slightly soluble; Methanol: Slightly soluble |
| form | A solid |
| pka | 16.10±0.46(Predicted) |
| CAS DataBase Reference | 306387-90-6 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Danger |
3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 20943 | Cyclopamine-KAAD ≥95% | 306387-90-6 | 500μg | $480 | 2024-03-01 | Buy |
| Cayman Chemical | 20943 | Cyclopamine-KAAD ≥95% | 306387-90-6 | 1mg | $869 | 2024-03-01 | Buy |
| TRC | K171000 | 3-Keto-N-aminoethyl-N’-aminocaproyldihydrocinnamoylCyclopamine | 306387-90-6 | 5mg | $510 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC158406 | Cyclopamine- KAAD | 306387-90-6 | 5mg | $800 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC158406 | Cyclopamine- KAAD | 306387-90-6 | 1mg | $250 | 2021-12-16 | Buy |
3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine Chemical Properties,Uses,Production
Chemical Properties
Pale Yellow Solid
Uses
Cyclopamine demonstrates teratogenic properties and has been shown to reverse effects ofoncogenic mutations in Smoothened and Patched.1 The KAAD derivative has shown 10-20 fold higher potency than cyclopamine in inhibition of ?-Galactosidase expression i
Uses
Cyclopamine demonstrates teratogenic properties and has been shown to reverse effects of oncogenic mutations in Smoothened and Patched.1 The KAAD-Cyclopamine has shown 10-20 fold higher potency than cyclopamine in inhibition of ?-Galactosidase expression in p2Ptch-1- cells, with similar or lower toxicity.KAAD-Cyclopamine compound is unstable in solution.
3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine Preparation Products And Raw materials
Raw materials
Preparation Products
3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine Suppliers
Global( 20)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 18521735133 18521732826; | market@aladdin-e.com | China | 25015 | 65 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8073 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55827 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
306387-90-6(3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine)Related Search:
3-Keto-N-aMinoethyl-N'-aMinocaproyldihydrocinnaMoyl CyclopaMine, >80%
Benzenepropanamide, N-[6-[[2-[(3'R,3'aS,6'S,6aS,6bS,7'aR,2'R,11aS,11bR)-1,2,3,3',3'a,4,5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-octadecahydro-3',6',10,11b-tetramethyl-3-oxospiro[9H-benzo[a]fluorene-9,2'(4'H)-furo[3,2-b]pyridin]-4'-yl]ethyl]amino]-6-oxohexyl]-
KAAD Cyclopamine,KAADCyclopamine
306387-90-6
C44H63N3O4
Inhibitors
Steroids
Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids