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Forskolin

Forskolin
Forskolin structure
CAS No.
66575-29-9
Chemical Name:
Forskolin
Synonyms
HL 362;CS-736;Forsklin;COLEONOL;Boforsin;ForsLean;FORSKOLIN;COLFORSIN;NSC 35708;Forskolii
CBNumber:
CB0167677
Molecular Formula:
C22H34O7
Formula Weight:
410.5
MOL File:
66575-29-9.mol

Forskolin Properties

Melting point:
282-232 °C
Boiling point:
520℃
alpha 
D25 -26.19° (c = 1.68 in CHCl3)
Density 
1.23
refractive index 
1.5300 (estimate)
Flash point:
172℃
storage temp. 
−20°C
solubility 
DMSO: 5 mg/mL stable at least 6 months at room temperature
form 
powder
pka
11.00±0.70(Predicted)
color 
off-white
Water Solubility 
Soluble in ethanol, dimethylsulfoxide and chloroform. Insolule in water.
λmax
305nm(lit.)
Merck 
14,2476
BRN 
1692716
InChIKey
OHCQJHSOBUTRHG-KGGHGJDLSA-N
CAS DataBase Reference
66575-29-9
EWG's Food Scores
1
FDA UNII
1F7A44V6OU
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Hazard statements  H303-H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xn
Risk Statements  21
Safety Statements  22-36/37
WGK Germany  3
RTECS  QL6150000
10-21
HS Code  29329990

Forskolin price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 344270 Forskolin 66575-29-9 10mg $181 2020-08-18 Buy
Sigma-Aldrich 1283244 Forskolin United States Pharmacopeia (USP) Reference Standard 66575-29-9 40mg $619 2021-03-22 Buy
TCI Chemical F0855 Forskolin >95.0%(HPLC) 66575-29-9 10mg $137 2021-03-22 Buy
TCI Chemical F0855 Forskolin >95.0%(HPLC) 66575-29-9 50mg $473 2021-03-22 Buy
Alfa Aesar J63292 Forskolin, 98+% 66575-29-9 10mg $156 2020-06-24 Buy

Forskolin Chemical Properties,Uses,Production

Chemical Properties

Colorless Crystalline Solid

Uses

Forskolin is a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP.

Uses

glucocorticoid, antiinflammatory

Uses

adenylate cyclase activator, antiglaucoma, hypotensive, vasodilator

Uses

Cyclic AMP (cAMP) is an important signal carrier necessary for the proper biological response of cells to hormones, neurotransmitters, and other extracellular signals Forskolin is a naturally occurring diterpene that is produced by the Indian Coleus plant (C. forskohlii). It directly activates adenylyl cyclase through its catalytic subunit and is commonly used to raise levels of cAMP in a wide variety of intact cells and tissue preparations. Forskolin binds to adenylyl cyclase in membranes from stably transfected Sf9 cells expressing type 1 adenylyl cyclase with an IC50 value of 41 nM and demonstrates an EC50 value of 0.5 μM in an activation assay assessing formation of cAMP from ATP. Forskolin also interacts with glucose transporters and certain ion channels and has been used for examining adenylyl cyclase expression, regulation, and G protein signaling.[Cayman Chemical]

Uses

An adenylate cyclase activator and MAP kinase inhibitor

Uses

In purification of adenylate cyclase.

Biological Activity

Cell-permeable activator of adenylyl cyclase. Hypotensive and vasodilatory agent. Induces neuronal differentiation in stem cells and in several neuroblastoma. Also available as part of the PKA Tocriset™ .

Purification Methods

It is an antihypertensive, a positive ionotropic, a platelet aggregation inhibitor, and it has adenylate cyclase activating properties [Chem Abstr 89 244150 1978, de Souza et al. Med Res Rev 3 201 1983, X-ray: Tandon et al. Indian J Chem 15B 880 1977]. [Beilstein 18/5 V 55.]

Forskolin Preparation Products And Raw materials

Raw materials

Preparation Products


Forskolin Suppliers

Global( 279)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Chengdu Biopurify Phytochemicals Ltd.
18482058008 18080483897
maggie@biopurify.com CHINA 2712 58
NanJing Spring & Autumn Biological Engineering CO., LTD.
0086 13815430202 0086 13815430202
sale02@cqherb.com CHINA 372 58
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21251 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 8875 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3013 60
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29983 58
Chengdu GLP biotechnology Co Ltd
13350802083 028-87075086
scglp@glp-china.com CHINA 1824 58
Biochempartner
0086-13720134139
candy@biochempartner.com CHINA 968 58

View Lastest Price from Forskolin manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-07-11 Forskolin
66575-29-9
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
2021-07-09 Forskolin
66575-29-9
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
2019-06-27 Forskolin 66575-29-9
66575-29-9
US $65.00 / g 10mg ≥98% 1000.00 KGS NanJing Spring & Autumn Biological Engineering CO., LTD.

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