Propargyl-PEG2-acid
- CAS No.
- 1859379-85-3
- Chemical Name:
- Propargyl-PEG2-acid
- Synonyms
- Alkyne-PEG2-COOH;CAS_1859379-85-3;Propargyl-PEG1-COOH;Propargyl-PEG2-acid;Propargyl-PEG1-C2-COOH;Propyne-PEG1-CH2CH2COOH;3-[2-(2-Propyn-1-yloxy)ethoxy]propanoic acid;3-(2-(Prop-2-yn-1-yloxy)ethoxy)propanoic acid;Propanoic acid, 3-[2-(2-propyn-1-yloxy)ethoxy]-
- CBNumber:
- CB03163104
- Molecular Formula:
- C8H12O4
- Molecular Weight:
- 172.18
- MDL Number:
- MFCD29764323
- MOL File:
- 1859379-85-3.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H335-H315-H318 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P280-P305+P351+P338-P310 |
Propargyl-PEG2-acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 901566 | Propargyl-PEG2-acid | 1859379-85-3 | 50MG | $221 | 2023-06-20 | Buy |
| BroadPharm | BP-23165 | Propargyl-PEG2-acid 98% | 1859379-85-3 | 100mg | $290 | 2021-12-16 | Buy |
| ChemScene | CS-0068466 | Propargyl-PEG2-acid ≥98.0% | 1859379-85-3 | 100mg | $300 | 2021-12-16 | Buy |
| Activate Scientific | AS104183 | 3-[2-(2-Propyn-1-yloxy)ethoxy]propanoic acid 95+% | 1859379-85-3 | 1g | $439 | 2021-12-16 | Buy |
| ChemScene | CS-0068466 | Propargyl-PEG2-acid ≥98.0% | 1859379-85-3 | 250mg | $450 | 2021-12-16 | Buy |
Propargyl-PEG2-acid Chemical Properties,Uses,Production
Description
Propargyl-PEG2-acid is a linker consisting of propargyl and carboxylic acid functional groups. In the presence of activators (e.g. EDC, or HATU), the carboxylic acid reacts with primary amine to form a stable amide bond. The propargyl group reacts with azide group in biomolecules to yield a stable triazole linkage.
Uses
Propargyl-PEG2-acid is a heterobifunctional, PEGylated crosslinker featuring a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG2-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.
Propargyl-PEG2-acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3149 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2893 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
View Lastest Price from Propargyl-PEG2-acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-26 | Propargyl-PEG2-acid
1859379-85-3
|
US $0.00 / g | 25g | >98.00% | 25g | Xian confluore Biological Technology Co., Ltd. |
-
- Propargyl-PEG2-acid
1859379-85-3
- US $0.00 / g
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
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