1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE
- CAS No.
- 484-49-1
- Chemical Name:
- 1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE
- Synonyms
- Olivacin;OLIVACINE;1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE;6H-Pyrido[4,3-B]carbazole, 1,5-dimethyl-;Inchi=1/C17H14N2/C1-10-12-7-8-18-11(2)14(12)9-15-13-5-3-4-6-16(13)19-17(10)15/H3-9,19H,1-2h
- CBNumber:
- CB0434720
- Molecular Formula:
- C17H14N2
- Molecular Weight:
- 246.31
- MDL Number:
- MFCD00189403
- MOL File:
- 484-49-1.mol
Melting point | 317-325° |
---|---|
FDA UNII | 5WSL5LL2C3 |
1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
American Custom Chemicals Corporation | PXT0001308 | 1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE 98.00% | 484-49-1 | 25MG | $1372.14 | 2021-12-16 | Buy |
AHH | MT-11009 | 1,5-Dimethyl-6H-pyrido[4,3-b]carbazole 99% | 484-49-1 | 1000g | $495 | 2021-12-16 | Buy |
1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE Chemical Properties,Uses,Production
Description
This alkaloid has recently been shown to exhibit a marked antineoplastic activity.
Administration of 25 or 50 mg/kg intraperitoneally on alternate days or daily until
death to mice which had been inoculated with a single intraperitoneal dose of
106 -102 LI2l0 leukemia cells increased the survival time by 89-229 per cent
compared with control animals.
Japanese workers have recently reported the synthesis of olivacine by heating
indole with 4(1-hydroxyethyl)-3-methoxymethyl-2-methylpyridine in 47 per
cent HBr.
Definition
ChEBI: Olivacine is a member of carbazoles.
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 27, p. 1751, 1990 DOI: 10.1002/jhet.5570270645
References
Regina et al., Cienc. Cult. (Sao Paulo), 26, 517 (1974)
Synthesis:
Kametani et al., J. Chern. Soc., Perkin I, 2102 (1975)
1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 | sales-cpd@caerulumpharma.com | China | 3466 | 58 |
Supplier | Advantage |
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ShangHai Caerulum Pharma Discovery Co., Ltd. | 58 |