C24-PHYTOCERAMIDE
- CAS No.
- 34437-74-6
- Chemical Name:
- C24-PHYTOCERAMIDE
- Synonyms
- C24-PHYTOCERAMIDE;N-24:0 Phytosphingosine;C24 Phytoceramide (t18:0/24:0);N-TETRACOSANOYL-PHYTOSPHINGOSINE;C24 Phytosphingosine (t18:0/24:0);N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-tetracosanamide;Tetracosanamide, N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-
- CBNumber:
- CB0788937
- Molecular Formula:
- C42H85NO4
- Molecular Weight:
- 668.13
- MDL Number:
- MFCD08703058
- MOL File:
- 34437-74-6.mol
C24-PHYTOCERAMIDE price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 22827 | C24 Phytosphingosine (t18:0/24:0) ≥98% | 34437-74-6 | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 22827 | C24 Phytosphingosine (t18:0/24:0) ≥98% | 34437-74-6 | 5mg | $184 | 2024-03-01 | Buy |
| AK Scientific | 7680CR | N-Tetracosanoylphytosphingosine | 34437-74-6 | 1mg | $147 | 2021-12-16 | Buy |
C24-PHYTOCERAMIDE Chemical Properties,Uses,Production
Description
C24 Phytoceramide (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis.1,2,3 C24 Phytoceramide (t18:0/24:0) is composed of a phytosphingosine backbone amine-linked to a C24 fatty acid chain. It has been used with other ceramides to create stratum corneum substitutes to study percutaneous penetration and psoriasis in vitro.4,5 In a stratum corneum model of healthy skin, the incorporation of long-chain-containing phytoceramides, such as C24 phytoceramide (t18:0/24:0), increases permeability of the membrane in comparison with incorporation of dihydroceramides.6
Definition
ChEBI: N-tetracosanoylphytosphingosine is a phytoceramide compound having a tetracosanoyl group attached to the nitrogen atom. It has a role as a Saccharomyces cerevisiae metabolite. It is a N-(very-long-chain fatty acyl)-sphingoid base and a N-acylphytosphingosine.
References
1. Crossman, M.W., and Hirschberg, C.B. Biosynthesis of phytosphingosine by the rat J. Biol. Chem. 252(16),5815-5819(1977).
2. Omae, F., Miyazaki, M., Enomoto, A., et al. DES2 protein is responsible for phytoceramide biosynthesis in the mouse small intestine Biochem J. 379(Pt. 3),687-695(2004).
3. Mizutani, Y., Kihara, A., and Igarashi, Y. Identification of the human sphingolipid C4-
4. de Jager, M., Groenink, W., van der Spek, J., et al. Preparation and characterization of a stratum corneum substitute for in vitro percutaneous penetration studies Biochim. Biophys. Acta 1758(5),636-644(2006).
5. Basse, L.H., Groen, D., and Bouwstra, J.A. Permeability and lipid organization of a novel psoriasis stratum corneum substitute Int. J. Pharm. 457(1),275-282(2013).
6. ?kolová, B., Ková?ik, A., Tesa?, O., et al. Phytosphingosine, sphingosine and dihydrosphingosine ceramides in model skin lipid membranes: Permeability and biophysics Biochim. Biophys. Acta 1859(5),824-834(2017).
C24-PHYTOCERAMIDE Preparation Products And Raw materials
C24-PHYTOCERAMIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| Yichang Zhongyitai Trading Co., Ltd. | 0717-6449896 13886658719 | root@zhongyitai.com | China | 1976 | 58 |
| Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9171 | 60 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Shanghai Universal Biotech Co.,Ltd | 18768175414 | gaojun@univ-bio.com | China | 24998 | 58 |
| amyjetsci | 027-59626688 18771149750 | sales@amyjet.com | China | 3004 | 58 |
| Shaanxi Didu New Material Co., Ltd | 029-63373950 15353716720 | 1052@dideu.com | China | 10004 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |