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ChemicalBook >> CAS DataBase List >>tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Structure
tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate structure
CAS No.
1201187-44-1
Chemical Name:
tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
Synonyms
tert-butyl N-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate;Upadacitinib Impurity 3;Upadacitinib Intermediate4;Upadacitinib intermediate2;Intermediate of Upadacitinib (ABT-494);2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine;tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate;N-[5-[(4-Methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-y...;tert-butyl (5-(p-toluenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl)carbamate;2-Methyl-2-propanyl {5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl}carbamate
CBNumber:
CB13102742
Molecular Formula:
C18H20N4O4S
Molecular Weight:
388.44
MDL Number:
MFCD28129728
MOL File:
1201187-44-1.mol
Last updated:2023-08-25 16:38:04
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tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Properties

Density 1.35±0.1 g/cm3(Predicted)
pka 9.45±0.43(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H317
Precautionary statements  P280

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B809575 tert-ButylN-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate 1201187-44-1 250mg $220 2021-12-16 Buy
Chemenu CM119289 2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine 95%+ 1201187-44-1 1g $310 2021-12-16 Buy
Chemenu CM119289 2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine 95%+ 1201187-44-1 5g $858 2021-12-16 Buy
Crysdot CD11333434 tert-Butyl(5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-yl)carbamate 97% 1201187-44-1 1g $1085 2021-12-16 Buy
Chemenu CM119289 2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine 95%+ 1201187-44-1 10g $1788 2021-12-16 Buy
Product number Packaging Price Buy
B809575 250mg $220 Buy
CM119289 1g $310 Buy
CM119289 5g $858 Buy
CD11333434 1g $1085 Buy
CM119289 10g $1788 Buy

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Chemical Properties,Uses,Production

Uses

tert-Butyl N-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate is a reagent in the synthetic preparation of tricyclic heterocycles and their kinase inhibitory activity. Preparation of novel nitrogen-containing tricyclic compounds as kinase inhibitors for treating immunological and oncological conditions.

Uses

Tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate, also known as upadacitinib intermediate 2, could be used in the synthesis and property studies of upadacitinib. This compound Often used as organic synthesis intermediates and pharmaceutical intermediates. It can be used in laboratory research processes and chemical production processes.

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate synthesis

4248-19-5
1201186-54-0
1201187-44-1
Synthesis of tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate from tert-Butyl carbamate and N-Tosyl-5-bromo-4,7-diazaindole

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Preparation Products And Raw materials

Raw materials

N-Tosyl-5-bromo-4,7-diazaindole tert-Butyl carbamate

Preparation Products

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Suppliers

Global( 197)Suppliers
Supplier Tel Email Country ProdList Advantage
Heading （Nanjing）Pharmtechnologies Co., Ltd.
+86-25-58467899-832 +86-13382406280 liucheng@headingpharm.com China 46 58
Hangzhou ICH Biofarm Co., Ltd 		+86-0571-28186870; +undefined8613073685410 sales@ichemie.com China 985 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20366 58
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1811 55
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21687 55
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9338 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32715 60
career henan chemical co 		+86-0371-86658258 15093356674; sales@coreychem.com China 29914 58
Zhejiang ZETian Fine Chemicals Co. LTD 		18957127338 stella@zetchem.com China 2141 58
Nanjing Dolon Biotechnology Co.,Ltd. 		18905173768 sales@dolonchem.com CHINA 2972 58
Supplier Advantage
Heading （Nanjing）Pharmtechnologies Co., Ltd.
58
Hangzhou ICH Biofarm Co., Ltd 		58
Henan Fengda Chemical Co., Ltd 		58
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
Henan Tianfu Chemical Co.,Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Zhejiang ZETian Fine Chemicals Co. LTD 		58
Nanjing Dolon Biotechnology Co.,Ltd. 		58

View Lastest Price from tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate pictures 2024-04-11 tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
1201187-44-1
 US $5.00-0.10 / KG 1KG 98% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
Carbamic acid, N-?[5-?[(4-?methylphenyl)?sulfonyl]?-?5H-?pyrrolo[2,?3-?b]?pyrazin-?2-?yl]?-?, 1,?1-?dimethylethyl ester pictures 2023-11-01 Carbamic acid, N-?[5-?[(4-?methylphenyl)?sulfonyl]?-?5H-?pyrrolo[2,?3-?b]?pyrazin-?2-?yl]?-?, 1,?1-?dimethylethyl ester
1201187-44-1
 US $0.00 / kg 1kg 99% 200kg Hangzhou ICH Biofarm Co., Ltd
tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate pictures 2023-11-01 tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
1201187-44-1
 US $0.00-0.00 / kg 0.1kg 99.0%min 200kg Hangzhou ICH Biofarm Co., Ltd

1201187-44-1(tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate)Related Search:

tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate tert-Butyl 3-phenyl-L-alaninate hydrochloride tert-Butyl 3-allyl-4-oxopyrrolidine-1-carboxylate (3R,4S)-3-(2-Bromoacetyl)-4-ethyl-1-pyrrolidinecarboxylic acid phenylmethyl ester
(3R,4S)-1-[(benzyloxy)carbonyl]-4-ethylpyrrolidine-3-carboxylic acid 5-[(4-methylphenyl)sulfonyl]-5H-Pyrrolo[2,3-b]pyrazin-2-amine 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate tert-Butyl (4-methylpiperidin-4-yl)carbamate tert-Butyl 3-oxoazetidine-1-carboxylate
tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate Upadacitinib

1of3

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Carbamic acid, N-?[5-?[(4-?methylphenyl)?sulfonyl]?-?5H-?pyrrolo[2,?3-?b]?pyrazin-?2-?yl]?-?, 1,?1-?dimethylethyl ester tert-butyl (5-(p-toluenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl)carbamate Intermediate of Upadacitinib (ABT-494) 2-Methyl-2-propanyl {5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl}carbamate Upadacitinib intermediate2 2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine N-[5-[(4-Methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-y... Upadacitinib Impurity 3 Upadacitinib Intermediate4 tert-butyl N-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate N-[5-[(4-Methylphenyl)sulfony!]-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamic, acid 1, 1-dimethylethyl ester 1201187-44-1