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SU 5205

CAS No.
3476-86-6
Chemical Name:
SU 5205
Synonyms
SU 5205;SU 5205; SU-5205; SU5205;2H-Indol-2-one, 3-[(4-fluorophenyl)methylene]-1,3-dihydro-;mitogenesis,Inhibitor,VEGFR2,Vascular endothelial growth factor receptor,FLK-1,SU-5205,endothelial,VEGFR,SU5205,inhibit
CBNumber:
CB13123194
Molecular Formula:
C15H10FNO
Molecular Weight:
239.24
MDL Number:
MOL File:
3476-86-6.mol
Last updated:2023-06-08 09:03:09

SU 5205 Properties

Melting point 194-196 °C
Boiling point 435.3±45.0 °C(Predicted)
Density 1.306±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMF: 50 mg/ml; DMSO: 50 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml; Ethanol: 5 mg/ml
form A crystalline solid
pka 12.69±0.20(Predicted)

SAFETY

Risk and Safety Statements

SU 5205 price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 27310 SU 5205 3476-86-6 100mg $106 2024-03-01 Buy
Cayman Chemical 27310 SU 5205 3476-86-6 250mg $199 2024-03-01 Buy
Cayman Chemical 27310 SU 5205 3476-86-6 50mg $63 2024-03-01 Buy
CSNpharm CSN20604 Su5205 3476-86-6 100mg $81 2021-12-16 Buy
Ambeed A425715 Su5205 97% 3476-86-6 10mg $86 2021-12-16 Buy
Product number Packaging Price Buy
27310 100mg $106 Buy
27310 250mg $199 Buy
27310 50mg $63 Buy
CSN20604 100mg $81 Buy
A425715 10mg $86 Buy

SU 5205 Chemical Properties,Uses,Production

Biological Activity

SU5205 is an inhibitor of VEGF receptor 2 (VEGFR2/FLK-1) with IC50 of 9.6 μM.

in vitro

SU5205 inhibits ligand-induced endothelial mitogenesis for VEGF with an IC 50 of 5.1 μM.

target

TargetValue
VEGFR2
(Cell-free assay)
9.6 μM

SU 5205 Preparation Products And Raw materials

Raw materials

Preparation Products

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SU 5205 2H-Indol-2-one, 3-[(4-fluorophenyl)methylene]-1,3-dihydro- SU 5205; SU-5205; SU5205 mitogenesis,Inhibitor,VEGFR2,Vascular endothelial growth factor receptor,FLK-1,SU-5205,endothelial,VEGFR,SU5205,inhibit 3476-86-6