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NIH-12848

CAS No.
959551-10-1
Chemical Name:
NIH-12848
Synonyms
NIH-12848;NIH-12848, >98%;NIH12848;NIH 12848;NIH-12848, 959551-10-1;NIH-12848,NIH12848,Inhibitor,inhibit,NIH 12848;4-Quinazolinamine, N-(2-thienylmethyl)-2-[2-(trifluoromethyl)phenyl]-;N-(thiophen-2-ylmethyl)-2-(2-(trifluoromethyl)phenyl)quinazolin-4-amine
CBNumber:
CB13161516
Molecular Formula:
C20H14F3N3S
Molecular Weight:
385.41
MDL Number:
MFCD30738011
MOL File:
959551-10-1.mol
Last updated:2023-06-08 09:03:09

NIH-12848 Properties

Boiling point 441.6±45.0 °C(Predicted)
Density 1.384±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 25 mg/mL
form A crystalline solid
pka 5.05±0.30(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
NFPA 704
0
2 0

NIH-12848 price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 26035 NIH 12848 959551-10-1 5mg $116 2024-03-01 Buy
Cayman Chemical 26035 NIH 12848 959551-10-1 25mg $353 2024-03-01 Buy
Cayman Chemical 26035 NIH 12848 959551-10-1 1mg $37 2024-03-01 Buy
Cayman Chemical 26035 NIH 12848 959551-10-1 10mg $161 2024-03-01 Buy
TRC N394020 NIH-12848 959551-10-1 10mg $115 2021-12-16 Buy
Product number Packaging Price Buy
26035 5mg $116 Buy
26035 25mg $353 Buy
26035 1mg $37 Buy
26035 10mg $161 Buy
N394020 10mg $115 Buy

NIH-12848 Chemical Properties,Uses,Production

Uses

NIH-12848 is a a putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor, and also a potentially powerful tool for exploring the cell physiology of PI5P4Ks. Reagent in the synthesis and structure-activity relationship studies of N-benzyl-2-phenylpyrimidin-4-amines as potent USP1/UAF1 deubiquitinase inhibitors with anticancer activity against nonsmall cell lung cancer.

27757-85-3
607-68-1
959551-10-1
Synthesis of NIH-12848 from 2-Thiophenemethylamine and 2,4-Dichloroquinazoline
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NIH-12848 NIH-12848, 959551-10-1 4-Quinazolinamine, N-(2-thienylmethyl)-2-[2-(trifluoromethyl)phenyl]- NIH-12848, >98% NIH12848;NIH 12848 N-(thiophen-2-ylmethyl)-2-(2-(trifluoromethyl)phenyl)quinazolin-4-amine NIH-12848,NIH12848,Inhibitor,inhibit,NIH 12848 959551-10-1 C20H14F3N3S